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Biotin-PEG4-alkyne - 95%, high purity , CAS No.1458576-00-5
Basic Description Synonyms Biotin-PEG4-Alkyne | Acetylene-PEG4-biotin conjugate | 1458576-00-5 | 1262681-31-1 | 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)pentanamide | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidaz Specifications & Purity 95% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Biotin-PEG4-alkyne is PEG derivative containing a biotin group and an alkyne group. The alkyne group can react with azide moiety in Cu(I)-catalyzed Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
Names and Identifiers IUPAC Name 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethyl]pentanamide INCHI InChI=1S/C21H35N3O6S/c1-2-8-27-10-12-29-14-15-30-13-11-28-9-7-22-19(25)6-4-3-5-18-20-17(16-31-18)23-21(26)24-20/h1,17-18,20H,3-16H2,(H,22,25)(H2,23,24,26)/t17-,18-,20-/m0/s1 InChi Key SKMJWNZZFUDLKQ-BJLQDIEVSA-N Canonical SMILES C#CCOCCOCCOCCOCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2 Isomeric SMILES C#CCOCCOCCOCCOCCNC(=O)CCCC[C@H]1[C@@H]2[C@H](CS1)NC(=O)N2 Alternate CAS 1262681-31-1 PubChem CID 75409985 Molecular Weight 457.6
Chemical and Physical Properties Solubility Solubility in Water, DMSO, DCM, DMF
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