Biotin-PEG4-NHS ester - 98%, high purity , CAS No.459426-22-3

Item Number

B595039

Grouped product items
SKU	Size	Availability	Price
B595039-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$256.90
B595039-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$462.90
B595039-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$832.90

Biotin-NHS ester

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Basic Description

Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Biotin-PEG4-NHS ester is PEG derivative containing a biotin group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS group reacts specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form stable amide bonds.

Names and Identifiers

IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
INCHI	InChI=1S/C25H40N4O10S/c30-20(4-2-1-3-19-24-18(17-40-19)27-25(34)28-24)26-8-10-36-12-14-38-16-15-37-13-11-35-9-7-23(33)39-29-21(31)5-6-22(29)32/h18-19,24H,1-17H2,(H,26,30)(H2,27,28,34)/t18-,19-,24-/m0/s1
InChi Key	DTLVBHCSSNJCMJ-JXQFQVJHSA-N
Canonical SMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3
Isomeric SMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@H]2[C@@H]3[C@H](CS2)NC(=O)N3
PubChem CID	59046443
Molecular Weight	588.67

Citations of This Product

1. Shuang-Qiang Liu, Zhi-Chen Mao, Yan-Li Xu, Xiao-Man Chen, Hui-Ling Wang, Qi Wang, Jian-Hua Wei, Ri-Zhen Huang, Ye Zhang. (2023) Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance. BIOORGANIC CHEMISTRY, 131 (106323). [PMID:36538834]

References

1. Shuang-Qiang Liu, Zhi-Chen Mao, Yan-Li Xu, Xiao-Man Chen, Hui-Ling Wang, Qi Wang, Jian-Hua Wei, Ri-Zhen Huang, Ye Zhang. (2023) Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance. BIOORGANIC CHEMISTRY, 131 (106323). [PMID:36538834]

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Basic Description