Bis(triphenylphosphine)palladium dichloride - Pd 15.2%, high purity , CAS No.13965-03-2

Item Number

D109544

• Synonyms: 13965-03-2|Dichlorobis(triphenylphosphine)palladium(II)|bis(triphenylphosphine)palladium(ii) chloride|Bis(triphenylphosphine)palladium(II) dichloride|MFCD00009593|PDCL2(PPH3)2|trans-dichlorobis(triphenylphosphine)palladium(ii)|bis(triphenylphosphine)palla
• Specifications & Purity: Pd 15.2%
• Storage Temp: Argon charged
• Shipped In: Normal

Product Description

Application

Bis(triphenylphosphine)palladium(II) dichloride is an organometallic complex. It is an efficient cross-coupling catalyst for C-C coupling reaction, such as Negishi coupling, Suzuki coupling, Sonogashira coupling and Heck coupling reaction.Detection of bis(triphenylphosphine)palladium(II) dichloride by electrospray ionization quadrupole ion trap mass spectrometry using different imidazolium salts as the charge carrier has been reported.It is employed as catalyst for the Heck reaction medium.
Bis(triphenylphosphine)palladium(II) dichloride is an organometallic complex. It is an efficient cross-coupling catalyst for C-C coupling reaction, such as Negishi coupling, Suzuki coupling, Sonogashira coupling and Heck coupling reaction.Detection of bis(triphenylphosphine)palladium(II) dichloride by electrospray ionization quadrupole ion trap mass spectrometry using different imidazolium salts as the charge carrier has been reported.It is employed as catalyst for the Heck reaction medium.
Palladium-catalyzed coupling of iodo-α-β-unsaturated esters to afford tetrasubstituted olefins

Product class

M-P, Homogeneous Catalysts, Monodentate Ligands, Phosphorus Ligands - Achiral

Reaction type

Cross Coupling Reactions with Arenes, Carbonylation, Mizoroki Heck Coupling Reaction, Sonogashira-Hagihara Coupling Reaction, Stille Reaction, Cyclization, Oxidation, Reduction

Chemical properties

Chemical formula

C36H30Cl2P2Pd

Empirical formula

[Pd(PPh3)2Cl2]

Molecular weight

701.91

Metal

Pd

Theoretical metal content

15

Physical state

powder

Color

yellow

Applications & references

Synthesis of the pyrazolopyridinone-based p38 mitogen-activated protein kinase inhibitor including a Suzuki coupling reaction. p38 MAP kinases are intercellular serine/threonine kinases which certainly regulate the production and action of several pro-inflammatory mediators. They are also involved in disease states such as rheumatoid arthritis, Crohn’s diseases and psoriasis.

Reference: Org. Proc. Res. Dev. 2011, 15, 31. (DOI: 10.1021/op100205s)

Mild and effective direct palladium catalyzed C-H alkynylation of electron-rich heterocycles.

Synthesis of spiro-indane-oxindoles with a tandem Heck / C-H functionalization.

Reference: Angew. Chem. Int. Ed. 2008, 47, 4711. (DOI: 10.1002/anie.200800549)

Palladium catalyzed intermolecular decarboxylative coupling in the presence of reactive C-H groups.

Reference: J. Org. Chem. 2010, 75, 1550. (DOI: 10.1021/jo9022793)

High yielding Palladium catalyzed C-H arylation of electron-enriched heteroarenes with aryl bromides.

Reference: J. Org. Chem. 2010, 75, 6998. (DOI: 10.1021/jo101433g)