Bisindolylmaleimide IV - 98% (TLC), high purity , CAS No.119139-23-0, Inhibitor of protein kinase C beta

Item Number

B166335

• Synonyms: bisindolylmaleimide iv|119139-23-0|3,4-di(1H-indol-3-yl)-1H-pyrrole-2,5-dione|Arcyriarubin A|3,4-Bis(3-indolyl)maleimide|3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione|3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione|1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-|BIM IV|C
• Specifications & Purity: Moligand™, ≥98%(TLC)
• Biochemical and Physiological Mechanisms: Potent cell-permeable PKC inhibitor (IC 50 values are 0.1 - 0.55 μM). Inhibits PKA (IC 50 values are 2 - 11.8 µM). Noncompetitive nAChR antagonist. Shows less potent antinicotinic effects than Bisindolylmaleimide II .
• Storage Temp: Room temperature
• Shipped In: Normal
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of protein kinase C beta
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.