I. Aladdin®Scientific Therapeutic Antibodies
Therapeutic antibodies are antibodies that are directed against a specific drug target.In the drug discovery process, therapeutic antibodies can be used to study the action mechanism、drug targets, and the interaction between the drug and the target.
Therapeutic antibodies have been developed and approved for the treatment of a variety of diseases, including cancer, autoimmune diseases, infectious diseases and inflammation.
II. Main Mechanisms of Action
i. Blocking or Inhibiting the Specific Binding of Receptors or Ligands
Antibodies can target specific molecules or receptors involved in the disease process to bind and inhibit their activity, blocking relevant signaling pathways, inhibiting receptor multimerization, and disrupting cell-cell interactions.
ii. Immune-enhancing Effect
Targeted antibodies stimulate the immune system to target and destroy specific cells or molecules.These include antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cell-mediated phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC).
iii. Blocking Immune Checkpoints
Immune checkpoint inhibitors such as CTLA-4, PD-L1, and CD96 block their receptor-mediated immune activation via antibodies, which in turn kills tumor cells.
iv. Transportation of Drugs or Toxins
Antibodies can be linked to small molecule drugs or toxins, and the drug or toxin can be delivered to specific cells or tissues through antibody targeting.This enhances the delivery and efficacy of the therapeutic agent while minimizing off-target effects.
III. Main Applications
i. Functional Assay
ii. ELISA
iii. FACS
iv. Animal model
IV. Why Aladdin Scientific?
i. Large quantity in stock, complete packages: Aladdin has 1mg, 5mg, 10mg and other packages to meet your different needs.
ii. Affordable price, high cost-effective: some products provide free trial packs.
iii. Self-application verification, more authoritative: the official website of Aladdin products has the relevant verification of the products, more reliable and authoritative.
Antibody-targeted drugs play a unique advantage and role in the diagnosis and treatment of diseases, especially for major diseases such as cancer, cardiovascular diseases and infections, showing great therapeutic potential and broad application prospects. Aladdin provides you with a wide range of therapeutic antibodies, and strict quality control relieves you from the worries of the products!
Welcome to visit our official website to learn more about Aladdin therapeutic antibodies.