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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B412587-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,608.90 | |
B412587-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $272.90 | |
B412587-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,886.90 | |
B412587-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,078.90 |
Synonyms | BLT-1|321673-30-7|[(2-hexylcyclopentylidene)amino]thiourea|2-hexyl-1-cyclopentanone thiosemicarbazone|33M20|Probes1_000008|Probes1_000093|Probes2_000390|Probes2_000409|(2Z)-2-(2-hexylcyclopentylidene)hydrazinecarbothioamide|CHEMBL3402568|SCHEMBL13560896|D |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | BLT-1 is an inhibitor of HDL receptor SR-BI. BLT-1 is primarily used for phosphorylation and dephosphorylation applications.Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description |
BLT-1 (Block lipid transport-1) has been used as an inhibitor of the SR-BI (scavenger receptor, class B, type I) mediated lipid transfer to determine if miR-223-3p export from polymorphonuclear neutrophils (PMNs) to high-density lipoproteins (HDLs) is dependent on SR-BI-mediated lipid flux. It has also been used as a SR-BI inhibitor to study the effect of HDL on osteocalcin (OCN) expression in monocyte cell lines through SR-B1.
BLT-1 may be used to study cell signaling pathways that have role in cholesterol influx and efflux.
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | [(E)-(2-hexylcyclopentylidene)amino]thiourea |
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INCHI | InChI=1S/C12H23N3S/c1-2-3-4-5-7-10-8-6-9-11(10)14-15-12(13)16/h10H,2-9H2,1H3,(H3,13,15,16)/b14-11+ |
InChi Key | OWGUSBISUVLUJF-SDNWHVSQSA-N |
Canonical SMILES | CCCCCCC1CCCC1=NNC(=S)N |
Isomeric SMILES | CCCCCCC\1CCC/C1=N\NC(=S)N |
WGK Germany | 3 |
PubChem CID | 9585336 |
Molecular Weight | 241.4 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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A2420068 | Certificate of Analysis | Dec 19, 2023 | B412587 |
A2420069 | Certificate of Analysis | Dec 19, 2023 | B412587 |
A2420070 | Certificate of Analysis | Dec 19, 2023 | B412587 |
A2420071 | Certificate of Analysis | Dec 19, 2023 | B412587 |
A2420072 | Certificate of Analysis | Dec 19, 2023 | B412587 |
Solubility | DMSO: ≥13 mg/mL |
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WGK Germany | 3 |
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RIDADR | NONHforallmodesoftransport |