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BM-1244 - 98%, high purity , CAS No.1619923-32-8

  • ≥98%
Item Number
B647821
Grouped product items
SKUSizeAvailabilityPrice Qty
B647821-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$500.90
B647821-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,100.90
B647821-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,700.90
B647821-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,200.90
View related series
Apoptosis Bcl-2 Family

Basic Description

Specifications & Purity98%
Storage TempStore at -20°C
Shipped InDry ice
Product Description

BM-1244 (APG-1252-M1) is a potent Bcl-xL / Bcl-2 inhibitor with K i s of 134 and 450 nM for Bcl- xL and Bcl-2 , respectively. BM-1244 inhibits senescent fibroblasts (SnCs) with an EC 50 of 5 nM. (From patent WO2019033119A1).

Form:Solid

Names and Identifiers

Canonical SMILES O=C(C1CCN(CC[C@@H](NC2=CC=C(S(=O)(NC3=CC=C(N4CCN(C5=CC(F)=CC(C6=C(C7=CC=C(Cl)C=C7)N(C(C)C)C(C)=C6S(=O)(C)=O)=C5)CC4)C=C3)=O)C=C2S(=O)(C(F)(F)F)=O)CSC8=CC=CC=C8)CC1)O
Molecular Weight 1159.79

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 200 mg/mL (172.45 mM; Need ultrasonic)

Related Documents

Solution Calculators