Bobcat339 hydrochloride - 99%, high purity , CAS No.2436747-44-1

Item Number

B651497

Grouped product items
SKU	Size	Availability	Price
B651497-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$250.90
B651497-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
B651497-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$950.90
B651497-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,500.90

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Basic Description

Specifications & Purity	99%
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice
Product Description	Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme , with the IC 50 s of 33 μM and 73 μM for TET1 and TET2 , respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription In Vitro Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:TET1 33 μM (IC 50 ) TET2 73 μM (IC 50 )

Names and Identifiers

IUPAC Name	4-amino-5-chloro-1-(3-phenylphenyl)pyrimidin-2-one;hydrochloride
INCHI	InChI=1S/C16H12ClN3O.ClH/c17-14-10-20(16(21)19-15(14)18)13-8-4-7-12(9-13)11-5-2-1-3-6-11;/h1-10H,(H2,18,19,21);1H
InChi Key	ZOMPKMMOPYMRIB-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)C2=CC(=CC=C2)N3C=C(C(=NC3=O)N)Cl.Cl
PubChem CID	138319672
Molecular Weight	334.20

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Basic Description