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Boc-Leu-Gly-Arg-AMC - 10mM in DMSO, high purity , CAS No.65147-09-3(DMSO)

  • 10mM in DMSO
Item Number
B655599
Grouped product items
SKUSizeAvailabilityPrice Qty
B655599-1ml
1ml
Available within 8-12 weeks(?)
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$215.90
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Amino Acid Derivatives

Basic Description

Specifications & Purity10mM in DMSO
Storage TempProtected from light,Desiccated,Store at -80°C
Shipped InDry ice
Product Description

Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays.

In Vitro

To demonstrate the presence in the abdominal gland of proteolytic enzymes capable of generating Sodefrin, an enzymatic assay was developed using Boc-Leu-Gly-Arg-AMC as synthetic substrate. A crude extract of the abdominal gland hydrolyzed Boc-Leu-Gly-Arg-AMC to liberate 7-amino-4- methylcoumarin, suggesting that enzymes that generate sodefrin from its precursor molecule are present in the gland. The activity in the extract for cleaving Boc-Leu-Gly-Arg-AMC is optimal at pH 9.0 and 45 ℃. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Names and Identifiers

Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)OC(C)(C)C
Molecular Weight 601.69

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