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Boc-Val-Cit-PAB - ≥97%, high purity , CAS No.870487-09-5

  • ≥97%
Item Number
B597026
Grouped product items
SKUSizeAvailabilityPrice Qty
B597026-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$146.90
B597026-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$249.90
B597026-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
B597026-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$669.90

Val-Cit

View related series
Peptide Linkers

Basic Description

Specifications & Purity≥97%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Boc-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell.

Names and Identifiers

IUPAC Name tert-butyl N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(hydroxymethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
INCHI InChI=1S/C23H37N5O6/c1-14(2)18(28-22(33)34-23(3,4)5)20(31)27-17(7-6-12-25-21(24)32)19(30)26-16-10-8-15(13-29)9-11-16/h8-11,14,17-18,29H,6-7,12-13H2,1-5H3,(H,26,30)(H,27,31)(H,28,33)(H3,24,25,32)/t17-,18-/m0/s1
InChi Key VYCVAPFXSOAOCL-ROUUACIJSA-N
Canonical SMILES CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)OC(C)(C)C
Isomeric SMILES CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)OC(C)(C)C
PubChem CID 59841854
Molecular Weight 479.57

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Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
H2416112Certificate of AnalysisMay 07, 2024 B597026
H2416113Certificate of AnalysisMay 07, 2024 B597026
H2416114Certificate of AnalysisMay 07, 2024 B597026
H2416115Certificate of AnalysisMay 07, 2024 B597026
H2416116Certificate of AnalysisMay 07, 2024 B597026
H2416117Certificate of AnalysisMay 07, 2024 B597026
H2416118Certificate of AnalysisMay 07, 2024 B597026
H2416119Certificate of AnalysisMay 07, 2024 B597026

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