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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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B647406-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $350.90 |
Phenols Polyphenols Others
Synonyms | boeravinone B|114567-34-9|6,9,11-trihydroxy-10-methyl-6H-chromeno[3,4-b]chromen-12-one|6a,12a-Dehydro-6,9,11-trihydroxy-10-methylrotenone|10-Methyl-6,9,11-trihydroxy[1]benzopyrano[3,4-b][1]benzopyran-12(6H)-one|boeravinoneB|CHEMBL376240|SCHEMBL3320676|Boe |
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Specifications & Purity | ≥97% |
Biochemical and Physiological Mechanisms | Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein , reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules duri |
Storage Temp | Protected from light,Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein , reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress. In Vitro Boeravinone B is also active against a methicillin-resistant S. aureus (MRSA) strain, which showed a fourfold reduction in the ciprofloxacin MIC. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
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IUPAC Name | 6,9,11-trihydroxy-10-methyl-6H-chromeno[3,4-b]chromen-12-one |
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INCHI | InChI=1S/C17H12O6/c1-7-9(18)6-11-13(14(7)19)15(20)12-8-4-2-3-5-10(8)23-17(21)16(12)22-11/h2-6,17-19,21H,1H3 |
InChi Key | YVVDYYFGAWQOGB-UHFFFAOYSA-N |
Canonical SMILES | CC1=C(C2=C(C=C1O)OC3=C(C2=O)C4=CC=CC=C4OC3O)O |
Isomeric SMILES | CC1=C(C2=C(C=C1O)OC3=C(C2=O)C4=CC=CC=C4OC3O)O |
Alternate CAS | 114567-34-9 |
PubChem CID | 14018348 |
MeSH Entry Terms | 6,9,11-trihydroxy-10-methyl-6a,12a-dehydroretenoid;boeravinone B |
Molecular Weight | 312.27 |
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Solubility | DMSO : 50 mg/mL (160.12 mM; Need ultrasonic) |
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