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Bradykinin Fragment 1-7 - ≥97% (HPLC), high purity , CAS No.23815-87-4

≥97%(HPLC)

CAS#: 23815-87-4
Formula: C₃₅H₅₂N₁₀O₉
Molecular Weight: 756.85
MDL number: MFCD00076262
PubChem CID: 168145

Item Number

B118779

Grouped product items
SKU	Size	Availability	Price	Qty
B118779-5mg	5mg	In stock	$147.90
B118779-25mg	25mg	In stock	$666.90

Basic Description

Synonyms	23815-87-4 \| BRADYKININ (1-7) \| Arg-Pro-Pro-Gly-Phe-Ser-Pro \| bradykinin 1-7 \| H-Arg-Pro-PRO-Gly-Phe-Ser-Pro-OH \| Des-8,9-BK \| 8-Des-phe-9-des-arg-BK \| Des-phe(8)-arg(9)-BK \| (2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]
Specifications & Purity	≥97% (HPLC)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Names and Identifiers

IUPAC Name	(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carboxylic acid
INCHI	InChI=1S/C35H52N10O9/c36-22(10-4-14-39-35(37)38)31(50)44-16-6-12-26(44)33(52)43-15-5-11-25(43)30(49)40-19-28(47)41-23(18-21-8-2-1-3-9-21)29(48)42-24(20-46)32(51)45-17-7-13-27(45)34(53)54/h1-3,8-9,22-27,46H,4-7,10-20,36H2,(H,40,49)(H,41,47)(H,42,48)(H,53,54)(H4,37,38,39)/t22-,23-,24-,25-,26-,27-/m0/s1
InChi Key	CRROPKNGCGVIOG-QCOJBMJGSA-N
Canonical SMILES	C1CC(N(C1)C(=O)C2CCCN2C(=O)C(CCCN=C(N)N)N)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)O
Isomeric SMILES	C1C[C@H](N(C1)C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)N)C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)O
WGK Germany	3
PubChem CID	168145
Molecular Weight	756.85

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2 results found

Lot Number	Certificate Type	Date	Item
K2005080	Certificate of Analysis	Aug 21, 2024	B118779
K2005081	Certificate of Analysis	Aug 21, 2024	B118779

References

1. M Simmaco,D De Biase,C Severini,M Aita,G F Erspamer,D Barra,F Bossa. (1990-03-26) Purification and characterization of bioactive peptides from skin extracts of Rana esculenta.. Biochimica et biophysica acta, 1033 ((3)): (318-323). [PMID:2317508]
2. M Katori,M Majima,R Odoi-Adome,N Sunahara,Y Uchida. (1989-12-01) Evidence for the involvement of a plasma kallikrein-kinin system in the immediate hypotension produced by endotoxin in anaesthetized rats.. British journal of pharmacology, 98 ((4)): (1383-1391). [PMID:2692754]
3. L Germain,J Barabe,C Galeano. (1988-02-01) Increased blood concentration of des-Arg9-bradykinin in experimental allergic encephalomyelitis.. Journal of the neurological sciences, 83 ((2-3)): (211-217). [PMID:3356989]
4. J M Ribeiro,T N Mather. (1998-06-27) Ixodes scapularis: salivary kininase activity is a metallo dipeptidyl carboxypeptidase.. Experimental parasitology, 89 ((2)): (213-221). [PMID:9635445]
5. M Bramucci,A Miano,A Gobbetti,M Zerani,L Quassinti,E Maccari,O Murri,D Amici. (2002-05-25) Bradykinin is not involved in angiotensin converting enzyme modulation of ovarian steroidogenesis and prostaglandin production in frog Rana esculenta.. Acta physiologica Scandinavica, 175 ((2)): (123-128). [PMID:12028132]
6. Darren Greetham,Charly Morgan,Alison M Campbell,Arjan J van Rossum,John Barrett,Peter M Brophy. (2004-06-29) Evidence of glutathione transferase complexing and signaling in the model nematode Caenorhabditis elegans using a pull-down proteomic assay.. Proteomics, 4 ((7)): (1989-1995). [PMID:15221760]
7. C Shima,M Majima,M Katori. (1992-10-01) A stable metabolite, Arg-Pro-Pro-Gly-Phe, of bradykinin in the degradation pathway in human plasma.. Japanese journal of pharmacology, 60 ((2)): (111-119). [PMID:1479739]
8. M Majima,A Ueno,N Sunahara,M Katori. (1989-01-01) Measurement of des-Phe8-Arg9-bradykinin by enzyme-immunoassay--a useful parameter of plasma kinin release.. Advances in experimental medicine and biology, 247B (331-335). [PMID:2692413]
9. L Germain,J Barabe,C Galeano. (1986-12-01) Blood levels of kinins in experimental allergic encephalomyelitis.. Journal of neuroimmunology, 13 ((2)): (135-142). [PMID:3782464]
10. Ch Golias,A Charalabopoulos,D Stagikas,K Charalabopoulos,A Batistatou. (2007-07-01) The kinin system--bradykinin: biological effects and clinical implications. Multiple role of the kinin system--bradykinin.. Hippokratia, 11 ((3)): (124-128). [PMID:19582206]
11. Laura M Jones,Katharina Staffa,Samïrah Perally,E James LaCourse,Peter M Brophy,Jo V Hamilton. (2010-04-16) Proteomic analyses of Caenorhabditis elegans dauer larvae and long-lived daf-2 mutants implicates a shared detoxification system in longevity assurance.. Journal of proteome research, 9 ((6)): (2871-2881). [PMID:20392130]

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