BRL-42715 , CAS No.B608222

Item Number

B608222

Grouped product items
SKU	Size	Availability	Price	Qty
B608222-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
B608222-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,500.90

Synonyms

C6-(N1-Methyl-1,2,3-trazolylmethylene)penem;LS-186900 (sodium salt);LS-187554

Grade

Moligand™

Names and Identifiers

IUPAC Name	(5R,6E)-6-[(1-methyltriazol-4-yl)methylidene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
INCHI	InChI=1S/C9H6N4O3S/c14-7-5(1-4-2-10-12-11-4)8-13(7)6(3-17-8)9(15)16/h1-3,8H,(H,15,16)(H,10,11,12)/b5-1+/t8-/m1/s1
InChi Key	WFUNKYVUHIZWEW-VRFQNRHZSA-N
Canonical SMILES	O=C1/C(=C\c2c[nH]nn2)/[C@@H]2N1C(=CS2)C(=O)O
Isomeric SMILES	CN1C=C(N=N1)/C=C\2/[C@@H]3N(C2=O)C(=CS3)C(=O)O
PubChem CID	6436245

PubChem CID

Antibiotic DB

References

1. Appelbaum PC, Spangler SK, Shiman R, Jacobs MR. (1992) Susceptibilities of 540 anaerobic gram-negative bacilli to amoxicillin, amoxicillin-BRL 42715, amoxicillin-clavulanate, temafloxacin, and clindamycin.. Antimicrob Agents Chemother, 36 (5): (1140-3). [PMID:1324639]
2. Ephtimios IE, Barrett MS, Wenzel RP, Jones RN. (1992) In-vitro antimicrobial activity of the penem BRL-42715, alone and in combination with ampicillin, against respiratory tract pathogens.. J Antimicrob Chemother, 29 (5): (599-600). [PMID:1624400]
3. Farmer TH, Page JW, Payne DJ, Knowles DJ. (1994) Kinetic and physical studies of beta-lactamase inhibition by a novel penem, BRL 42715.. Biochem J, 303 ( Pt 3) (3): (825-30). [PMID:7980451]
4. Muratani T, Yokota E, Nakane T, Inoue E, Mitsuhashi S. (1993) In-vitro evaluation of the four beta-lactamase inhibitors: BRL42715, clavulanic acid, sulbactam, and tazobactam.. J Antimicrob Chemother, 32 (3): (421-9). [PMID:8262864]
5. Aldridge KE. (1993) A new potent beta-lactamase inhibitor, BRL 42715, with inherent activity against Bacteroides fragilis group strains.. Clin Infect Dis, 16 Suppl 4 (3): (S335-8). [PMID:8324143]

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Basic Description