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Butyric acid - for synthesis, high purity , CAS No.107-92-6, Agonist of FFA2 receptor;Agonist of FFA3 receptor;Agonist of HCA 2 receptor;Inhibitor of histone deacetylase 1;Inhibitor of histone deacetylase 2;Inhibitor of histone deacetylase 3;Inhibitor of histone deacetylase 8

for synthesis
Moligand™

CAS#: 107-92-6
Formula: C₄H₈O₂
Molecular Weight: 88.11
Beilstein Registry Number: 2264
EC Number: MFCD00002814
PubChem CID: 264

Item Number

B431361

Grouped product items
SKU	Size	Availability	Price	Qty
B431361-100ml	100ml	In stock	$9.90

View related series

FFA2 receptor Agonist FFA3 receptor Agonist HCA2 receptor Agonist histone deacetylase 1 Inhibitor histone deacetylase 2 Inhibitor histone deacetylase 3 Inhibitor histone deacetylase 8 Inhibitor

Basic Description

Synonyms	butyric acid\|butanoic acid\|107-92-6\|n-Butyric acid\|n-Butanoic acid\|propylformic acid\|ethylacetic acid\|1-propanecarboxylic acid\|butyrate\|Butanic acid\|1-Butyric acid\|Buttersaeure\|butanoate\|Butyric acid (natural)\|Kyselina maselna\|FEMA No. 2221\|Propanecarboxy
Specifications & Purity	Moligand™, for synthesis
Storage Temp	Room temperature
Shipped In	Normal
Grade	for synthesis, Moligand™
Action Type	AGONIST, INHIBITOR
Mechanism of action	Agonist of FFA2 receptor;Agonist of FFA3 receptor;Agonist of HCA 2 receptor;Inhibitor of histone deacetylase 1;Inhibitor of histone deacetylase 2;Inhibitor of histone deacetylase 3;Inhibitor of histone deacetylase 8

Associated Targets

DCXR Tbio L-xylulose reductase 0 Activities

Discover Target: DCXR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC22A6 Tclin Solute carrier family 22 member 6 0 Activities

Discover Target: SLC22A6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FFAR2 Tchem Free fatty acid receptor 2 0 Activities

Discover Target: FFAR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HCAR2 Tclin Hydroxycarboxylic acid receptor 2 1 Activities

Discover Target: HCAR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC4 Tclin Histone deacetylase 4 0 Activities

Discover Target: HDAC4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC1 Tclin Histone deacetylase 1 1 Activities

Discover Target: HDAC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC7 Tclin Histone deacetylase 7 0 Activities

Discover Target: HDAC7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC9 Tclin Histone deacetylase 9 0 Activities

Discover Target: HDAC9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC2 Tclin Histone deacetylase 2 1 Activities

Discover Target: HDAC2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FIBCD1 Tbio Fibrinogen C domain-containing protein 1 0 Activities

Discover Target: FIBCD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FFAR3 Tchem Free fatty acid receptor 3 0 Activities

Discover Target: FFAR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A10 Tbio UDP-glucuronosyltransferase 1-10 0 Activities

Discover Target: UGT1A10

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UGT1A8 Tbio UDP-glucuronosyltransferase 1-8 0 Activities

Discover Target: UGT1A8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PKM Tchem Pyruvate kinase PKM 0 Activities

Discover Target: PKM

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC8 Tclin Histone deacetylase 8 1 Activities

Discover Target: HDAC8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC5 Tclin Histone deacetylase 5 0 Activities

Discover Target: HDAC5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC3 Tclin Histone deacetylase 3 1 Activities

Discover Target: HDAC3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC16A1 Tchem Monocarboxylate transporter 1 0 Activities

Discover Target: SLC16A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	butanoic acid
INCHI	InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
InChi Key	FERIUCNNQQJTOY-UHFFFAOYSA-N
Canonical SMILES	CCCC(=O)O
Isomeric SMILES	CCCC(=O)O
WGK Germany	1
RTECS	ES5425000
PubChem CID	264
UN Number	2820
Packing Group	III
Molecular Weight	88.11
Beilstein	2264
Reaxy-Rn	906770

Database links

PubChem CID	264
DrugBank Ligand	DB03568
CAS Registry No.	107-92-6
ChEBI	CHEBI:30772
Wikipedia	Butyric_acid
ChEMBL Ligand	CHEMBL14227
BindingDB Ligand	26109
RCSB PDB Ligand	BUA
GPCRdb Ligand	butyric acid

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot Number	Certificate Type	Date	Item
C2425033	Certificate of Analysis	Mar 28, 2024	B431361
E2331117	Certificate of Analysis	Jun 06, 2023	B431361
E2331124	Certificate of Analysis	Jun 06, 2023	B431361

Chemical and Physical Properties

Refractive Index	1.3965-1.3995
Flash Point(°F)	161 °F
Flash Point(°C)	72℃
Boil Point(°C)	162-165°C
Melt Point(°C)	-7--5°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H314:Causes severe skin burns and eye damage
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	1
RTECS	ES5425000
Reaxy-Rn	906770
Class	8
Merck Index	1593

References

1. Fass DM, Shah R, Ghosh B, Hennig K, Norton S, Zhao WN, Reis SA, Klein PS, Mazitschek R, Maglathlin RL et al.. (2010) Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.. ACS Med Chem Lett, 2 (1): (39-42). [PMID:21874153]
2. Verma MS, Fink MJ, Salmon GL, Fornelos N, Ohara TE, Ryu SH, Vlamakis H, Xavier RJ, Stappenbeck TS, Whitesides GM. (2018) A Common Mechanism Links Activities of Butyrate in the Colon.. ACS Chem Biol, 13 (5): (1291-1298). [PMID:29584955]

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