[¹¹C]JNJ-16567083 , CAS No.C613772, Antagonist of mGlu 1 receptor;Antagonist of mGlu 5 receptor

Item Number

C613772

Grouped product items
SKU	Size	Availability	Price	Qty
C613772-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$600.90
C613772-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Synonyms

[¹¹C]-JNJ-16567083

Grade

Moligand™

Action Type

ANTAGONIST

Mechanism of action

Antagonist of mGlu 1 receptor;Antagonist of mGlu 5 receptor

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	3-ethyl-6-[(4-methoxycyclohexyl)carbonyl]-2-(¹¹C)methylquinoline
INCHI	InChI=1S/C20H25NO2/c1-4-14-11-17-12-16(7-10-19(17)21-13(14)2)20(22)15-5-8-18(23-3)9-6-15/h7,10-12,15,18H,4-6,8-9H2,1-3H3/i2-1
InChi Key	VEURHZYLLRSEGL-JVVVGQRLSA-N
Canonical SMILES	COC1CCC(CC1)C(=O)c1ccc2c(c1)cc(c(n2)[11CH3])CC
Isomeric SMILES	CCC1=C(N=C2C=CC(=CC2=C1)C(=O)C3CCC(CC3)OC)[11CH3]
PubChem CID	9972691

References

1. Huang Y, Narendran R, Bischoff F, Guo N, Zhu Z, Bae SA, Lesage AS, Laruelle M. (2005) A positron emission tomography radioligand for the in vivo labeling of metabotropic glutamate 1 receptor: (3-ethyl-2-[11C]methyl-6-quinolinyl)(cis- 4-methoxycyclohexyl)methanone.. J Med Chem, 48 (16): (5096-9). [PMID:16078827]

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Basic Description