Coumetarol - 99%, high purity , CAS No.4366-18-1

  • ≥99%
Item Number
C647002
Grouped product items
SKUSizeAvailabilityPrice Qty
C647002-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$90.90
C647002-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$150.90
C647002-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$290.90
C647002-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$480.90
C647002-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$750.90

Basic Description

SynonymsDicumoxane; Ph 137 | 4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2-one | UO1VQB3SPZ | Coumetarol [INN:BAN:DCF] | Coumetarolum [INN-Latin] | COUMETAROL [MI] | Cumetarolo | Cumetarolo [DCIT] | Coumetarolum | MS-26213 | 3,3'-(2-Methox
Specifications & Purity≥99%
Biochemical and Physiological MechanismsCoumetarol (Dicumoxane) is a vitamin K antagonist.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Coumetarol (Dicumoxane) is a vitamin K antagonist.

In Vitro

Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:vitamin K

Names and Identifiers

IUPAC Name 4-hydroxy-3-[1-(4-hydroxy-2-oxochromen-3-yl)-2-methoxyethyl]chromen-2-one
INCHI InChI=1S/C21H16O7/c1-26-10-13(16-18(22)11-6-2-4-8-14(11)27-20(16)24)17-19(23)12-7-3-5-9-15(12)28-21(17)25/h2-9,13,22-23H,10H2,1H3
InChi Key BUCJFFQZPGTGPX-UHFFFAOYSA-N
Canonical SMILES COCC(C1=C(C2=CC=CC=C2OC1=O)O)C3=C(C4=CC=CC=C4OC3=O)O
Isomeric SMILES COCC(C1=C(C2=CC=CC=C2OC1=O)O)C3=C(C4=CC=CC=C4OC3=O)O
PubChem CID 54716150
Molecular Weight 380.35

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 250 mg/mL (657.29 mM; Need ultrasonic)

Related Documents

Solution Calculators