Cabamiquine succinate - 99%, high purity , CAS No.2444781-71-7

Item Number

C646406

Grouped product items
SKU	Size	Availability	Price
C646406-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$240.90
C646406-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$380.90
C646406-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$800.90
C646406-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,280.90

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Basic Description

Specifications & Purity	99%
Storage Temp	Store at 2-8°C,Protected from light,Desiccated
Shipped In	Wet ice
Product Description	Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite , with an EC 50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII , with an EC 50 of 2 nM for WT- Pf eEF2 In Vivo Cabamiquine (DDD107498) exhibits an ED 90 of 0.57 mg/kg after a single oral dose in mice infected with the rodent parasite P. berghei . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CaMK III Plasmodium

Names and Identifiers

IUPAC Name	butanedioic acid;6-fluoro-2-[4-(morpholin-4-ylmethyl)phenyl]-N-(2-pyrrolidin-1-ylethyl)quinoline-4-carboxamide
INCHI	InChI=1S/C27H31FN4O2.C4H6O4/c28-22-7-8-25-23(17-22)24(27(33)29-9-12-31-10-1-2-11-31)18-26(30-25)21-5-3-20(4-6-21)19-32-13-15-34-16-14-32;5-3(6)1-2-4(7)8/h3-8,17-18H,1-2,9-16,19H2,(H,29,33);1-2H2,(H,5,6)(H,7,8)
InChi Key	OTKHBNSZSWWVRJ-UHFFFAOYSA-N
Canonical SMILES	C1CCN(C1)CCNC(=O)C2=CC(=NC3=C2C=C(C=C3)F)C4=CC=C(C=C4)CN5CCOCC5.C(CC(=O)O)C(=O)O
PubChem CID	138319698
Molecular Weight	580.65

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Basic Description