Determine the necessary mass, volume, or concentration for preparing a solution.
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Basic Description
| Synonyms | caffeic acid|3,4-Dihydroxycinnamic acid|331-39-5|trans-caffeic acid|501-16-6|3,4-Dihydroxybenzeneacrylic acid|3-(3,4-dihydroxyphenyl)acrylic acid|(E)-3-(3,4-dihydroxyphenyl)acrylic acid|(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid|Caffeicacid|Cinnamic ac |
|---|---|
| Specifications & Purity | Moligand™, ≥98% |
| Shipped In | Normal |
| Grade | Moligand™ |
Associated Targets
CTH Tchem Cystathionine gamma-lyase 0 Activities
CYP3A4 Tclin Cytochrome P450 3A4 0 Activities
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DPP4 Tclin Dipeptidyl peptidase 4 0 Activities
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ESR1 Tclin Estrogen receptor 0 Activities
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DUSP3 Tchem Dual specificity protein phosphatase 3 0 Activities
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EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities
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EGFR Tclin Epidermal growth factor receptor 0 Activities
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CA5A Tclin Carbonic anhydrase 5A, mitochondrial 0 Activities
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PTPN11 Tchem Tyrosine-protein phosphatase non-receptor type 11 0 Activities
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HSP90AA1 Tchem Heat shock protein HSP 90-alpha 0 Activities
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HDAC6 Tclin Histone deacetylase 6 0 Activities
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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities
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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities
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TTR Tclin Transthyretin 0 Activities
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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities
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PTGS2 Tclin Prostaglandin G/H synthase 2 0 Activities
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MMP9 Tchem Matrix metalloproteinase-9 2 Activities
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MMP2 Tchem 72 kDa type IV collagenase 1 Activities
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GAA Tclin Lysosomal alpha-glucosidase 0 Activities
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CA5B Tclin Carbonic anhydrase 5B, mitochondrial 0 Activities
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CA6 Tclin Carbonic anhydrase 6 0 Activities
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CA13 Tclin Carbonic anhydrase 13 0 Activities
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CA1 Tclin Carbonic anhydrase 1 0 Activities
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CA3 Tclin Carbonic anhydrase 3 0 Activities
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CA2 Tclin Carbonic anhydrase 2 0 Activities
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CA4 Tclin Carbonic anhydrase 4 0 Activities
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CA12 Tclin Carbonic anhydrase 12 0 Activities
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CA14 Tclin Carbonic anhydrase 14 0 Activities
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CA9 Tclin Carbonic anhydrase 9 0 Activities
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CA7 Tclin Carbonic anhydrase 7 0 Activities
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BACE1 Tchem Beta-secretase 1 0 Activities
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XDH Tclin Xanthine dehydrogenase/oxidase 0 Activities
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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities
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ACHE Tclin Acetylcholinesterase 0 Activities
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MPG Tchem DNA-3-methyladenine glycosylase 0 Activities
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AKR1C3 Tchem Aldo-keto reductase family 1 member C3 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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AKR1B1 Tclin Aldose reductase 0 Activities
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ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities
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APP Tclin Amyloid-beta A4 protein 0 Activities
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SI Tchem Sucrase-isomaltase, intestinal 0 Activities
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F2 Tclin Prothrombin 0 Activities
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BCHE Tclin Cholinesterase 0 Activities
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KCNK2 Tclin Potassium channel subfamily K member 2 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities
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KDM4A Tchem Lysine-specific demethylase 4A 0 Activities
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MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities
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Names and Identifiers
| Pubchem Sid | 488191139 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488191139 |
| IUPAC Name | (E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid |
| INCHI | InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+ |
| InChi Key | QAIPRVGONGVQAS-DUXPYHPUSA-N |
| Canonical SMILES | C1=CC(=C(C=C1C=CC(=O)O)O)O |
| Isomeric SMILES | C1=CC(=C(C=C1/C=C/C(=O)O)O)O |
| WGK Germany | 3 |
| RTECS | GD8950000 |
| Alternate CAS | 501-16-6 |
| PubChem CID | 689043 |
| Molecular Weight | 180.16 |
| Beilstein | 1954563 |
Database links
| PubChem SID | 488191139 |
|---|
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 E2428187 | Certificate of Analysis | Jun 05, 2024 | C108306 |
| E2428186 | Certificate of Analysis | Jun 05, 2024 | C108306 |
| E2428157 | Certificate of Analysis | Jun 05, 2024 | C108306 |
| C2405303 | Certificate of Analysis | Mar 12, 2024 | C108306 |
| C2405304 | Certificate of Analysis | Mar 12, 2024 | C108306 |
| A2425135 | Certificate of Analysis | Jan 31, 2024 | C108306 |
| L2312025 | Certificate of Analysis | Dec 14, 2023 | C108306 |
| H2330218 | Certificate of Analysis | Sep 04, 2023 | C108306 |
| H2330214 | Certificate of Analysis | Sep 04, 2023 | C108306 |
| H2330179 | Certificate of Analysis | Sep 04, 2023 | C108306 |
| H2330211 | Certificate of Analysis | Sep 04, 2023 | C108306 |
| H2330212 | Certificate of Analysis | Sep 04, 2023 | C108306 |
| H2330213 | Certificate of Analysis | Sep 04, 2023 | C108306 |
| G2308171 | Certificate of Analysis | Jul 17, 2023 | C108306 |
| D2328186 | Certificate of Analysis | May 09, 2023 | C108306 |
| D2328189 | Certificate of Analysis | May 09, 2023 | C108306 |
| D2328191 | Certificate of Analysis | May 09, 2023 | C108306 |
| D2328200 | Certificate of Analysis | May 09, 2023 | C108306 |
| D2328173 | Certificate of Analysis | May 09, 2023 | C108306 |
| D2328183 | Certificate of Analysis | May 09, 2023 | C108306 |
| C2215103 | Certificate of Analysis | Mar 30, 2022 | C108306 |
| F2305985 | Certificate of Analysis | Mar 30, 2022 | C108306 |
| C2215105 | Certificate of Analysis | Mar 30, 2022 | C108306 |
| C2215106 | Certificate of Analysis | Mar 30, 2022 | C108306 |
more
Chemical and Physical Properties
| Solubility | Slightly soluble in water; Very soluble in Alcohol; Very slightly soluble in Chloroform |
|---|---|
| Sensitivity | Moisture sensitive. |
| Melt Point(°C) | 194-198°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H319:Causes serious eye irritation H351:Suspected of causing cancer |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. |
| WGK Germany | 3 |
| RTECS | GD8950000 |
| Merck Index | 1635 |