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Calindol hydrochloride - ≥98%, high purity , CAS No.729610-18-8
a new calcimimetic compound acting at the calcium sensing receptor
Basic Description Synonyms (1R)-N-(1H-indol-2-ylmethyl)-1-naphthalen-1-ylethanamine;hydrochloride | (1R)-N-[(1H-Indol-2-yl)methyl]-1-(naphthalen-1-yl)ethan-1-amine--hydrogen chloride (1/1) | (R)-2-[[[1-(1-Naphthyl)ethyl]amino]methyl]-1H-indole Hydrochloride | AS-57849 | AKOS0302545 Specifications & Purity ≥98% Storage Temp Store at 2-8°C Shipped In Wet ice Product Description Calindol hydrochloride is a new calcimimetic compound acting at the calcium sensing receptor. It is a positive allosteric modulator of the human Ca|2+|receptor which activates an extracellular ligand-binding domain-deleted, Rhodopsin-like, seven-transmembrane structure in the absence of Ca|2+|.
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (1R)-N-(1H-indol-2-ylmethyl)-1-naphthalen-1-ylethanamine;hydrochloride INCHI InChI=1S/C21H20N2.ClH/c1-15(19-11-6-9-16-7-2-4-10-20(16)19)22-14-18-13-17-8-3-5-12-21(17)23-18;/h2-13,15,22-23H,14H2,1H3;1H/t15-;/m1./s1 InChi Key KFILKQPBQZIRST-XFULWGLBSA-N Canonical SMILES CC(C1=CC=CC2=CC=CC=C21)NCC3=CC4=CC=CC=C4N3.Cl Isomeric SMILES C[C@H](C1=CC=CC2=CC=CC=C21)NCC3=CC4=CC=CC=C4N3.Cl PubChem CID 23544608 Molecular Weight 336.86
Chemical and Physical Properties Solubility Soluble in Chloroform and Methanol Melt Point(°C) 208-210° C (dec.)
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