Caracemide - 10mM in DMSO, high purity , CAS No.81424-67-1(DMSO)

  • 10mM in DMSO
Item Number
C654538
Grouped product items
SKUSizeAvailabilityPrice Qty
C654538-1ml
1ml
Available within 8-12 weeks(?)
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$495.90

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide is a novel anticancer agent derived from a hydroxamic acid and has demonstrated to produce severe central nervous system (CNS) toxicity.

In Vitro

Caracemide inactivates R1 by covalent modification at the substrate-binding site and has a toxic metabolite, methylisocyanate (MIC), in vivo . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

The mercapturic acid derivative AMCC was identified in urine rats following administration to rats of a single i.p. dose (6.6 mg/kg) of caracemide (NSC-253272) . . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Names and Identifiers

Canonical SMILES CC(N(OC(NC)=O)C(NC)=O)=O
Molecular Weight 189.17

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