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Carboplatin - 98%, high purity , CAS No.41575-94-4 Specifications & Purity: 98%
Antitumor agent; blocks DNA replication and transcription. Cisplatin analog.
Basic Description Synonyms 41575-94-4|Carboplatin|Paraplatin|Cbdca|Carboplatinum|MFCD00070464|NSC-241240|cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)|cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)|1,1-Cyclobutanedicarboxylate diammine platinum(II)|cis-Diammine(1,1 Specifications & Purity 98% Storage Temp Protected from light,Store at -20°C Shipped In Dry ice
Names and Identifiers IUPAC Name azanide;cyclobutane-1,1-dicarboxylic acid;platinum(2+) INCHI InChI=1S/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H2;/q;2*-1;+2 InChi Key VSRXQHXAPYXROS-UHFFFAOYSA-N Canonical SMILES C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2] Isomeric SMILES C1CC(C1)(C(=O)O)C(=O)O.[NH2-].[NH2-].[Pt+2] WGK Germany 3 RTECS TP2300000 Alternate CAS 41575-94-4 PubChem CID 426756 NSC Number 201345 MeSH Entry Terms Blastocarb;Carboplat;Carboplatin;Carbosin;Carbotec;CBDCA;cis-Diammine(cyclobutanedicarboxylato)platinum II;Ercar;JM 8;JM-8;JM8;Nealorin;Neocarbo;NSC 241240;NSC-241240;NSC241240;Paraplatin;Paraplatine;Platinwas;Ribocarbo Molecular Weight 371.25 Reaxy-Rn 13598388
Chemical and Physical Properties Solubility Soluble in water.DMSO can inactivate Carboplatin's activity. Sensitivity Light sensitive. Melt Point(°C) >275℃
Safety and Hazards(GHS) Pictogram(s) GHS08,GHS07 Signal Danger Hazard Statements H315,H319,H302,H317,H334,H312,H332,H372,H360,H340,H302+H312+H332,H362 Precautionary Statements P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P260,P284,P281,P271,P270,P304+P340,P272,P333+P313,P362+P364,P330,P263,P203,P264+P265,P301+P317,P318,P317,P337+P317,P332+P317,P319,P342+P316 WGK Germany 3 RTECS TP2300000 Reaxy-Rn 13598388 Merck Index 1822
References 1. Gonzalez Rajal A et al.. (2021) A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma.. Elife, 10 [PMID:33983115 ] 2. Hastings JF et al.. (2020) Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma.. Elife, 9 [PMID:32513387 ] 3. Ke FY et al.. (2020) Novel monoclonal antibody against integrin a3 shows therapeutic potential for ovarian cancer.. Cancer Sci, 111 (10): (3478-3492). [PMID:32648337 ]
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D2411199
