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Carboxymethyl chitosan - Degree of substitution: ≥90%, high purity , CAS No.83512-85-0
Basic Description Synonyms Carboxymethyl chitosan|83512-85-0|N-[(2S,3R,4R,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide|MFCD00677440|N Specifications & Purity Degree of substitution: ≥90% Storage Temp Store at 2-8°C,Desiccated Shipped In Wet ice Product Description Product Application:
Chitosan offers remarkable biological properties, it has been widely used in drug delivery and tissue engineering applications. Chitosan derivatives have unique properties including biocompatibility, mucoadhesion, non-toxicity, and capability to form gels. Furthermore, they are suitable candidates to manufacture films, tablets, and nanotechnology-based systems which have the possibility for commercial production as well as industrial scale-up. Chemical modification of CS chains using the carboxymethyl moieties will alter the water solubility due to the carboxymethylation degree. The carboxymethyl chitosan derivatives can also interact with cells for applications in cell growth, tissue regeneration, and wound healing.
Names and Identifiers IUPAC Name N-[(2S,3R,4R,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide INCHI InChI=1S/C20H37N3O14/c1-5(27)23-11-15(31)17(36-19-10(22)13(29)12(28)6(2-24)34-19)8(4-26)35-20(11)37-16-7(3-25)33-18(32)9(21)14(16)30/h6-20,24-26,28-32H,2-4,21-22H2,1H3,(H,23,27)/t6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16?,17?,18-,19+,20+/m1/s1 InChi Key HGNQXZLWHDQLRE-XADFZESNSA-N Canonical SMILES CC(=O)NC1C(C(C(OC1OC2C(OC(C(C2O)N)O)CO)CO)OC3C(C(C(C(O3)CO)O)O)N)O Isomeric SMILES CC(=O)N[C@@H]1[C@H](C([C@H](O[C@H]1OC2[C@H](O[C@H]([C@@H]([C@H]2O)N)O)CO)CO)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)N)O PubChem CID 71306969
Chemical and Physical Properties Sensitivity Heat, light and moisture sensitive
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
References 1. Yaoxun Zeng, Xinyi Li, Fangzheng Chen, Huiling Ye, Keyi Rong, Zhili Ran, Binhong Liu, Zhenxing Pan, Xiuxian Xie, Junze Tang, Xujie Liu, Yan He. (2024) Biomineralization-inspired porous calcium carbonate microspheres as a controlled release system of herbicides/pesticides. Journal of Environmental Chemical Engineering, 12 (3): (112572). [PMID: ]
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