The Bcl-2 family is divided into three subfamilies based on the number and arrangement of their Bcl-2 homology (BH) domains: the anti-apoptotic proteins (Bcl-2, Bcl-xL, Mcl-1, A1/Bfl-1), the pro-apoptotic BH3-only proteins (Bid, Bim, Bad, Puma, Noxa), and the pro-apoptotic multi-domain effector proteins (Bax, Bak).
B-cell lymphoma 2 (Bcl-2) protein family
ABT-737, Antagonist of BCL2 apoptosis regulator;Antagonist of Bcl-2-like 1;Antagonist of Bcl-2-like 2Cas#:852808-04-9
Starting at $81.90
AZD5991, Inhibitor of MCL1 apoptosis regulator; BCL2 family memberCas#:2143010-83-5
Starting at $454.90
AZD5991, Inhibitor of MCL1 apoptosis regulator; BCL2 family memberCas#:2143061-82-7
Starting at $922.90
- AZD4320, Inhibitor of BCL2 apoptosis regulator;Inhibitor of Bcl-2-like 1
Cas#:1357576-48-7
Starting at $1,334.90
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