Protein Degrader Building Blocks

Cas#: 209736-59-4        Compound CID:  71306285

Formula:  C₁₀H₁₇BrO₅S        Molecular Weight: 329.21

IUPAC Name: [(1S,3S,4S)-3-bromo-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid;hydrate

SMILES: CC1(C2CCC1(C(=O)C2Br)CS(=O)(=O)O)C.O

InChIKey: RQZLIPHNDCFLPR-OFVIFIGMSA-N

InChI: InChI=1S/C10H15BrO4S.H2O/c1-9(2)6-3-4-10(9,5-16(13,14)15)8(12)7(6)11;/h6-7H,3-5H2,1-2H3,(H,13,14,15);1H2/t6-,7+,10-;/m1./s1

Cas#: 958635-15-9        Compound CID:  23655051

Formula:  C₆H₁₁ClN₂O₂        Molecular Weight: 178.62

IUPAC Name: (8aS)-1,5,6,7,8,8a-hexahydro-[1,3]oxazolo[3,4-a]pyrazin-3-one;hydrochloride

SMILES: C1CN2C(CN1)COC2=O.Cl

InChIKey: NEFDJLDMYYSLHW-JEDNCBNOSA-N

InChI: InChI=1S/C6H10N2O2.ClH/c9-6-8-2-1-7-3-5(8)4-10-6;/h5,7H,1-4H2;1H/t5-;/m0./s1

Cas#: 147636-36-0        Compound CID:  737840

Formula:  C₁₃H₁₇NO₄S        Molecular Weight: 283.34

IUPAC Name: 1-(4-methylphenyl)sulfonylpiperidine-4-carboxylic acid

SMILES: CC1=CC=C(C=C1)S(=O)(=O)N2CCC(CC2)C(=O)O

InChIKey: YJRQMKSUAIKDDF-UHFFFAOYSA-N

InChI: InChI=1S/C13H17NO4S/c1-10-2-4-12(5-3-10)19(17,18)14-8-6-11(7-9-14)13(15)16/h2-5,11H,6-9H2,1H3,(H,15,16)

Cas#: 1256359-09-7        Compound CID:  53216819

Formula:  C₁₄H₁₉BN₂O₂        Molecular Weight: 258.13

IUPAC Name: 1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole

SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)C=NN3C

InChIKey: SHPRKJZVUGXCTM-UHFFFAOYSA-N

InChI: InChI=1S/C14H19BN2O2/c1-13(2)14(3,4)19-15(18-13)11-7-6-10-9-16-17(5)12(10)8-11/h6-9H,1-5H3

Cas#: 1029439-02-8        Compound CID:  54759098

Formula:  C₁₂H₁₆BFO₃        Molecular Weight: 238.1

IUPAC Name: 3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

SMILES: B1(OC(C(O1)(C)C)(C)C)C2=C(C=C(C=C2)O)F

InChIKey: ASYQJYIEVNXWDV-UHFFFAOYSA-N

InChI: InChI=1S/C12H16BFO3/c1-11(2)12(3,4)17-13(16-11)9-6-5-8(15)7-10(9)14/h5-7,15H,1-4H3

Cas#: 40117-63-3        Compound CID:  66737825

Formula:  C₈H₁₄ClNO₂        Molecular Weight: 191.66

IUPAC Name: 1-azabicyclo[2.2.2]octane-4-carboxylic acid;hydrochloride

SMILES: C1CN2CCC1(CC2)C(=O)O.Cl

InChIKey: JTYXRFSULOZNPH-UHFFFAOYSA-N

InChI: InChI=1S/C8H13NO2.ClH/c10-7(11)8-1-4-9(5-2-8)6-3-8;/h1-6H2,(H,10,11);1H

Cas#: 117836-13-2        Compound CID:  10913298

Formula:  C₁₅H₁₇NO₅        Molecular Weight: 291.303

IUPAC Name: 1-O-benzyl 2-O-methyl (2S)-5-oxopiperidine-1,2-dicarboxylate

SMILES: COC(=O)C1CCC(=O)CN1C(=O)OCC2=CC=CC=C2

InChIKey: HFKHJRQXLOFHNO-ZDUSSCGKSA-N

InChI: InChI=1S/C15H17NO5/c1-20-14(18)13-8-7-12(17)9-16(13)15(19)21-10-11-5-3-2-4-6-11/h2-6,13H,7-10H2,1H3/t13-/m0/s1

Cas#: 188847-00-9        Compound CID:  11346067

Formula:  C₁₄H₁₇NO₄        Molecular Weight: 263.293

IUPAC Name: 1-O-benzyl 3-O-methyl pyrrolidine-1,3-dicarboxylate

SMILES: COC(=O)C1CCN(C1)C(=O)OCC2=CC=CC=C2

InChIKey: JZDIVDBVWXFEMR-UHFFFAOYSA-N

InChI: InChI=1S/C14H17NO4/c1-18-13(16)12-7-8-15(9-12)14(17)19-10-11-5-3-2-4-6-11/h2-6,12H,7-10H2,1H3

Cas#: 1306829-95-7        Compound CID:  53375434

Formula:  C₆H₅BrN₄S        Molecular Weight: 245.1

IUPAC Name: 3-bromo-6-methylsulfanyl-2H-pyrazolo[3,4-d]pyrimidine

SMILES: CSC1=NC2=NNC(=C2C=N1)Br

InChIKey: PBEIXBIKEFRPGU-UHFFFAOYSA-N

InChI: InChI=1S/C6H5BrN4S/c1-12-6-8-2-3-4(7)10-11-5(3)9-6/h2H,1H3,(H,8,9,10,11)

Cas#: 1357946-70-3        Compound CID:  72207123

Formula:  C₆H₃BrClN₃        Molecular Weight: 232.465

IUPAC Name: 3-bromo-6-chloro-2H-pyrazolo[3,4-b]pyridine

SMILES: C1=CC(=NC2=NNC(=C21)Br)Cl

InChIKey: RLPKMCBJXWGFGK-UHFFFAOYSA-N

InChI: InChI=1S/C6H3BrClN3/c7-5-3-1-2-4(8)9-6(3)11-10-5/h1-2H,(H,9,10,11)

Cas#: 57120-36-2        Compound CID:  11159518

Formula:  C₁₀H₁₅NO        Molecular Weight: 165.23

IUPAC Name: 4-[(2-methylpropan-2-yl)oxy]aniline

SMILES: CC(C)(C)OC1=CC=C(C=C1)N

InChIKey: NJLJXOXRYXXBOF-UHFFFAOYSA-N

InChI: InChI=1S/C10H15NO/c1-10(2,3)12-9-6-4-8(11)5-7-9/h4-7H,11H2,1-3H3