Antiviral Signaling

The natural immune system is the first physiological defense line for the body to resist the invasion of pathogenic microorganisms, which plays an important role in limiting viral infection. It relies on several sets of pattern recognition receptors to recognize viral nucleic acids. The signal pathways mediated by RIG-I-MAVS and cGAS-STING play an important role in the natural immune response against RNA and DNA viruses, respectively.

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