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Innate Immunity

Innate immunity is the body’s first line of defense against pathogens and other harmful substances. It is essentially made up of barriers that aim to keep viruses, bacteria, parasites, and other foreign particles out of your body or limit their ability to spread and move throughout the body. The innate immune system includes physical barriers such as skin, the gastrointestinal tract, the respiratory tract, and the urinary tract. It also includes chemical barriers such as enzymes in tears and skin oils that kill bacteria. The innate immune system relies on the recognition of particular types of molecules that are common to many pathogens but are absent in the host. These pathogen-associated molecules stimulate two types of innate immune responses—inflammatory responses and phagocytosis by cells such as neutrophils and macrophages.

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Items 1-36 of 879

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  1. Goat Anti-Rabbit IgG H&L (APC)
      Application:
    • IF/ICC
    Species reactivity(Reacts with): Rabbit
    Host species: Goat    Conjugation: APC   
    Synonyms:Goat Anti-Rabbit IgG H&L Antibody (APC) | Anti-Rabbit IgG H&L Antibody (APC) | Rabbit IgG H&L Antibody (APC) | APC -c...
  2. Gardiquimod diTFA
      Grade & Purity:
    • ≥99%
    Cas#:1159840-61-5        Compound CID : 44592365
    Formula: C21H25F6N5O5        Molecular Weight:541.4
    IUPAC Name:1-[4-amino-2-(ethylaminomethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol;2,2,2-trifluoroacetic acid
    SMILES:CCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O
    InChIKey:XFQPQSJDMJVOBN-UHFFFAOYSA-N
    InChI:XFQPQSJDMJVOBN-UHFFFAOYSA-N
    Synonyms:1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-[(ethylamino)methyl]-alpha,alpha-dimethyl-, 2,2,2-trifluoroacetate (1...
  3. S18-000003
      Grade & Purity:
    • ≥99%
    Cas#:2068119-11-7        Compound CID : 137796283
    Formula: C26H25F3N2O4S        Molecular Weight:518.55
    IUPAC Name:N-(2,4-difluorophenyl)-2-[4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]-2-fluorophenyl]-2-methylpropanamide
    SMILES:CCS(=O)(=O)C1=CC=C(C=C1)CC(=O)NC2=CC(=C(C=C2)C(C)(C)C(=O)NC3=C(C=C(C=C3)F)F)F
    InChIKey:DZUAIKQCQQBQJM-UHFFFAOYSA-N
    InChI:DZUAIKQCQQBQJM-UHFFFAOYSA-N
  4. K6PC-5
      Grade & Purity:
    • ≥99%
    Cas#:756875-51-1        Compound CID : 11660192
    Formula: C19H37NO4        Molecular Weight:343.5
    IUPAC Name:N-(1,3-dihydroxypropan-2-yl)-2-hexyl-3-oxodecanamide
    SMILES:CCCCCCCC(=O)C(CCCCCC)C(=O)NC(CO)CO
    InChIKey:CGYVFCHCRBGGJG-UHFFFAOYSA-N
    InChI:CGYVFCHCRBGGJG-UHFFFAOYSA-N
    Synonyms:9UO46U4GM1 | DTXSID50997113 | HY-124042 | N-(1,3-dihydroxypropan-2-yl)-2-hexyl-3-oxodecanamide | UNII-9UO46U4GM1 | F8...
  5. XY101
      Grade & Purity:
    • ≥98%
    Cas#:2349368-16-5        Compound CID : 138105957
    Formula: C25H20F7NO4S        Molecular Weight:563.48
    IUPAC Name:2-(4-ethylsulfonylphenyl)-N-[4-[2-fluoro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]phenyl]acetamide
    SMILES:CCS(=O)(=O)C1=CC=C(C=C1)CC(=O)NC2=CC=C(C=C2)C3=C(C=C(C=C3)C(C(F)(F)F)(C(F)(F)F)O)F
    InChIKey:AUIAOCHKUNGZHV-UHFFFAOYSA-N
    InChI:AUIAOCHKUNGZHV-UHFFFAOYSA-N
  6. Sparstolonin B
      Grade & Purity:
    • ≥99%
    Cas#:1259330-61-4        Compound CID : 135659042
    Formula: C15H8O5        Molecular Weight:268.22
    IUPAC Name:4,14-dihydroxy-8,15-dioxatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2(7),3,5,9(17),10,13-heptaen-12-one
    SMILES:C1=CC2=C(C=C1O)C3=COC(=C4C3=C(O2)C=CC4=O)O
    InChIKey:KUPDHLFGNQEASI-UHFFFAOYSA-N
    InChI:KUPDHLFGNQEASI-UHFFFAOYSA-N
  7. GNE-6468
      Grade & Purity:
    • ≥98%
    Cas#:1677668-27-7        Compound CID : 117964975
    Formula: C23H16ClN3O4        Molecular Weight:433.84
    IUPAC Name:4-[6-(2-chloro-6-cyclopropylbenzoyl)imidazo[1,5-a]pyrimidin-8-yl]-2-hydroxybenzoic acid
    SMILES:C1CC1C2=C(C(=CC=C2)Cl)C(=O)C3=NC(=C4N3C=CC=N4)C5=CC(=C(C=C5)C(=O)O)O
    InChIKey:GIYKJPISDNWSJD-UHFFFAOYSA-N
    InChI:GIYKJPISDNWSJD-UHFFFAOYSA-N
  8. PF-06747711
      Grade & Purity:
    • ≥99%
    Cas#:1892576-58-7        Compound CID : 118977746
    Formula: C26H26F3N5O2        Molecular Weight:497.51
    IUPAC Name:3-cyano-N-[1-methyl-3-[1-(2-methylpropanoyl)piperidin-4-yl]-4-(trifluoromethyl)pyrrolo[2,3-b]pyridin-5-yl]benzamide
    SMILES:CC(C)C(=O)N1CCC(CC1)C2=CN(C3=NC=C(C(=C23)C(F)(F)F)NC(=O)C4=CC=CC(=C4)C#N)C
    InChIKey:BIHPJIJLDNUDGH-UHFFFAOYSA-N
    InChI:BIHPJIJLDNUDGH-UHFFFAOYSA-N
  9. G140
      Grade & Purity:
    • ≥98%
    Cas#:2369751-07-3        Compound CID : 139388865
    Formula: C17H16Cl2N4O2        Molecular Weight:379.24
    IUPAC Name:1-[6,7-dichloro-9-(1-methylpyrazol-3-yl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-hydroxyethanone
    SMILES:CN1C=CC(=N1)C2=CC(=C(C3=C2C4=C(N3)CCN(C4)C(=O)CO)Cl)Cl
    InChIKey:NVPFAXHXXODQRO-UHFFFAOYSA-N
    InChI:NVPFAXHXXODQRO-UHFFFAOYSA-N
  10. RO8191
      Grade & Purity:
    • ≥98%
    Cas#:691868-88-9        Compound CID : 2768133
    Formula: C14H5F6N5O        Molecular Weight:373.21
    IUPAC Name:2-[2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridin-8-yl]-1,3,4-oxadiazole
    SMILES:C1=CC2=NC(=CN2C3=C1C(=CC(=N3)C(F)(F)F)C(F)(F)F)C4=NN=CO4
    InChIKey:GRHYZVJEXKTJOS-UHFFFAOYSA-N
    InChI:GRHYZVJEXKTJOS-UHFFFAOYSA-N
    Synonyms:F77218 | NCGC00408901-01 | AKOS005079117 | CS-0055822 | MixCom2_000289 | 2-(2,4-bis(trifluoromethyl)imidazo[1,2-a][1,...
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