Thyroid axis

Cas#: 484-17-3        Compound CID:  10229

Formula:  C₁₄H₁₀O        Molecular Weight: 194.23

IUPAC Name: phenanthren-9-ol

SMILES: C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O

InChIKey: DZKIUEHLEXLYKM-UHFFFAOYSA-N

InChI: InChI=1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H

Associated targets:  TPO

Species reactivity(Reacts with):  Human

Host species:  Rabbit    Isotype:  Rabbit IgG   

Species reactivity(Reacts with):  Human

Cas#: 2242751-53-5(DMSO)       

Formula:  C₁₅H₁₈ClFN₂O₃        Molecular Weight: 328.77

SMILES: CC1=C(C(=NN1)C)CCCOC2=C(C=CC(=C2)C(=O)O)F.Cl

Species reactivity(Reacts with):  Human

Cas#: 1432726-13-0        Compound CID:  121493436

Molecular Weight: 7601.00

SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=S)([O-])O[C@H]3C[C@@H](O[C@@H]3COP(=S)([O-])O[C@H]4C[C@@H](O[C@@H]4COP(=S)([O-])O[C@@H]5[C@H](O[C@H]([C@@H]5OCCOC)N6C=NC7=C6N=C(NC7=O)N)COP(=S)([O-])O[C@@H]8[C@H](O[C@H]([C@@H]8OCCOC)N9C=C(C(=O)NC9=O)C)COP(=S)([O-])O[C@@H]1[C@H](O[C@H]([C@@H]1OCCOC)N1C=C(C(=O)NC1=O)C)COP(=O)(O[C@@H]1[C@H](O[C@H]([C@@H]1OCCOC)N1C=C(C(=NC1=O)N)C)COP(=S)([O-])O[C@@H]1[C@H](O[C@H]([C@@H]1OCCOC)N1C=C(C(=O)NC1=O)C)CO)[S-])N1C=NC2=C1N=C(NC2=O)N)N1C=C(C(=O)NC1=O)C)OP(=S)([O-])OC[C@@H]1[C@H](C[C@@H](O1)N1C=NC2=C(N=CN=C21)N)OP(=S)([O-])OC[C@@H]1[C@H](C[C@@H](O1)N1C=C(C(=NC1=O)N)C)OP(=S)([O-])OC[C@@H]1[C@H](C[C@@H](O1)N1C=NC2=C(N=CN=C21)N)OP(=S)([O-])OC[C@@H]1[C@H](C[C@@H](O1)N1C=C(C(=O)NC1=O)C)OP(=S)([O-])OC[C@@H]1[C@H](C[C@@H](O1)N1C=NC2=C1N=C(NC2=O)N)OP(=S)([O-])OC[C@@H]1[C@H](C[C@@H](O1)N1C=NC2=C(N=CN=C21)N)OP(=S)([O-])OC[C@@H]1[C@H](C[C@@H](O1)N1C=NC2=C(N=CN=C21)N)OP(=S)([O-])OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C=NC2=C(N=CN=C21)N)OCCOC)OP(=S)([O-])OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C=C(C(=O)NC1=O)C)OCCOC)OP(=S)([O-])OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C=C(C(=NC1=O)N)C)OCCOC)OP(=S)([O-])OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C=C(C(=NC1=O)N)C)OCCOC)OP(=S)([O-])OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C=C(C(=NC1=O)N)C)OCCOC)O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

Species reactivity(Reacts with):  Human

Cas#: 1867157-35-4(free)       

Formula:  C₅₃₀H₇₁₅F₉N₁₇₁O₃₂₃P₄₃S₆(free)        Molecular Weight: 16345.00(free)

Species reactivity(Reacts with):  Human

Cas#: 1386913-72-9       

Molecular Weight: 13427.10 (AS: 6661.3; SS: 6765.8)

SMILES: [Patisiran (sodium)]

Species reactivity(Reacts with):  Human

Cas#: 951395-08-7(DMSO)       

Formula:  C₂₁H₂₄Cl₂N₂O₈        Molecular Weight: 503.33

SMILES: CNCC(C(C(C(CO)O)O)O)O.C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl

Species reactivity(Reacts with):  Human

Molecular Weight: 6661.3

SMILES: [AS-Patisiran]

Associated targets:  NRGN NACA

Species reactivity(Reacts with):  Human,Mouse

Host species:  Mouse    Isotype:  Mouse IgG1   

Species reactivity(Reacts with):  Human,Mouse

Species: Human   

Expression system: HEK293   

Protein Tag: C-His   

Accession #: Q03431   

Endotoxin Concentration: <0.1 EU/μg   

Associated targets:  TPO

Species reactivity(Reacts with):  Human

Host species:  Mouse    Isotype:  Mouse IgG2b   

Associated targets:  FDX1

Species reactivity(Reacts with):  Human,Mouse,Rat

Host species:  Rabbit    Isotype:  Rabbit IgG