The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It is a hetero-oligomer composed of a large extracellular portion, which associates in a calcium-dependent, non-covalent interaction with a smaller piece of the notch protein composed of a short extracellular region, a single transmembrane-pass, and a small intracellular region.
Notch Pathway
PHA-767491, Inhibitor of MAPK activated protein kinase 2;Inhibitor of ribosomal protein S6 kinase A4Cas#:845714-00-3
Starting at $209.90
Alsterpaullone, Inhibitor of cyclin dependent kinase 1;Inhibitor of glycogen synthase kinase 3 betaCas#:237430-03-4
Starting at $256.90
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- SB415286, Inhibitor of glycogen synthase kinase 3 alpha;Inhibitor of glycogen synthase kinase 3 beta
Cas#:264218-23-7
Starting at $14.90
- GF109203X, Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C beta;Inhibitor of protein kinase C gamma
Cas#:133052-90-1
Starting at $18.90
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- SB216763, Inhibitor of glycogen synthase kinase 3 alpha;Inhibitor of glycogen synthase kinase 3 beta
Cas#:280744-09-4
Starting at $64.90
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