CBWD2 Antibody - Primary antibody, specific to ZNG1B, Rabbit IgG
Synonyms
CBWD2_HUMAN antibody | Cobalamin synthase W domain-containing protein 2 antibody | Cobalamin synthetase W domain-containing protein 2 antibody | COBW domain-containing protein 2 antibody | ZNG1B | CBWD2 | CBWD2 antibody
Specifications & Purity
ExactAb™, Validated, 1.0 mg/mL
Host species
Rabbit
Specificity
ZNG1B
Immunogen
A synthetic peptide derived from human CBWD2 (AA 108-158)
Positive Control
WB: Rat lung, U-2 OS, HeLa and THP-1 lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Validated
Product Description
Rabbit anti Human CBWD2 Antibody, Polyclonal, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1B to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active METAP1.
Product Properties
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Immunogen affinity purified
Form
Liquid
Concentration
1.0 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
CBWD2 Antibody (Ab093328) - Western Blot All lanes: CBWD2 Antibody (Ab093328) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 43 kDa Observed band size: 42 kDa Exposure time: 30.0 s