CC-99677 - 98%, high purity , CAS No.1887069-10-4

  • ≥98%
Item Number
C651896
Grouped product items
SKUSizeAvailabilityPrice Qty
C651896-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$850.90
C651896-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,300.90
View related series
MAPK/ERK Pathway MAPKAPK2 (MK2)

Basic Description

Specifications & Purity≥98%
Biochemical and Physiological MechanismsCC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 ( MK2 ) pathway in both biochemical ( IC 50 =156.3 nM) and cell based assays ( EC 50 =89 nM). CC-99677 is extracted from pa
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 ( MK2 ) pathway in both biochemical ( IC 50 =156.3 nM) and cell based assays ( EC 50 =89 nM). CC-99677 is extracted from patent WO2020236636, compound 1

In Vitro

CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 ( MK2 ) pathway in both biochemical ( IC 50 =156.3 nM) and cell based assays ( EC 50 =89 nM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:MK2

Names and Identifiers

Canonical SMILES CCOCC1=CN=C(N=C1OC2=NC3=C(C=C2)C4=C(C=C3)SC5=C4NC[C@H](NC5=O)C)Cl
Isomeric SMILES CCOCC1=CN=C(N=C1OC2=NC3=C(C=C2)C4=C(C=C3)SC5=C4NC[C@H](NC5=O)C)Cl
PubChem CID 118936948
Molecular Weight 469.94

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 37.5 mg/mL (79.80 mM; ultrasonic and warming and heat to 60°C)

Related Documents

Solution Calculators