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CCDC47 Antibody

  • Carrier Free
  • ExactAb™
  • Validated
  • 0.8 mg/mL
Features and benefits
  • Short Overview:

    pAb; Rabbit anti Human CCDC47 Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab093389
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab093389-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
Ab093389-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
Ab093389-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$379.90
Ab093389-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,899.90

pAb; Rabbit anti Human CCDC47 Antibody; WB, IHC; Unconjugated

Basic Description

Product NameCCDC47 Antibody
Specifications & PurityExactAb™, Validated, Carrier Free, 0.8 mg/mL
Host speciesRabbit
SpecificityCCDC47
ImmunogenFusion protein of human CCDC47 (AA 264-483)
Positive ControlWB: K562, HeLa, HEK293, Jurkat, NIH/3T3 and C6 cell lysates. IHC: Human tonsil tissue.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human CCDC47 Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions. Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein (By similarity). Within the PAT subcomplex, CCDC47 occludes the lateral gate of the SEC61 complex (By similarity). Involved in the regulation of calcium ion homeostasis in the ER. Required for proper protein degradation via the ERAD (ER-associated degradation) pathway. Has an essential role in the maintenance of ER organization during embryogenesis (By similarity).

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified
FormLiquid
Concentration0.8 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

CCDC47 Antibody (Ab093389) - Western Blot
All lanes: CCDC47 Antibody (Ab093389) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 56 kDa
Observed band size: 58 kDa
Exposure time: 8.1 s

CCDC47 Antibody (Ab093389) - IHC
Immunohistochemistry analysis of paraffin-embedded Human tonsil using CCDC47 Antibody (Ab093389). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets

CCDC47 Tbio Coiled-coil domain-containing protein 47 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

1/50 - 1/100

WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Solution Calculators