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CCG 1423 - ≥99%(HPLC), high purity , CAS No.285986-88-1

  • Moligand™
  • ≥99%(HPLC)
Item Number
C288630
Grouped product items
SKUSizeAvailabilityPrice Qty
C288630-10mg
10mg
In stock
$64.90
C288630-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$207.90
C288630-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$936.90

Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs

View related series
cancer research

Basic Description

SynonymsCCG-1423|285986-88-1|CCG1423|CCG 1423|n-(2-(4-chloroanilino)-1-methyl-2-oxoethoxy)-3,5-bis(trifluoromethyl)benzamide|N-((1-((4-chlorophenyl)amino)-1-oxopropan-2-yl)oxy)-3,5-bis(trifluoromethyl)benzamide|N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(
Specifications & PurityMoligand™, ≥99%(HPLC)
Biochemical and Physiological MechanismsRho/SRF pathway inhibitor; stimulates apoptosis of a melanoma cell line overexpressing RhoC (A375M2). Suppresses Rho-dependent invasion of PC-3 prostate cancer cellsin vitroand inhibits lysophosphatidic acid-induced DNA synthesis in PC-3 prostate cancer c
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
GradeMoligand™

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide
INCHI InChI=1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29)
InChi Key DSMXVSGJIDFLKP-UHFFFAOYSA-N
Canonical SMILES CC(C(=O)NC1=CC=C(C=C1)Cl)ONC(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F
Isomeric SMILES CC(C(=O)NC1=CC=C(C=C1)Cl)ONC(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F
PubChem CID 2726015
Molecular Weight 454.75

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
J2119322Certificate of AnalysisAug 09, 2024 C288630
J2119334Certificate of AnalysisAug 09, 2024 C288630
J2119351Certificate of AnalysisAug 09, 2024 C288630

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 45.48, Max Conc. mM: 100
Sensitivityheat sensitive

Related Documents

References

1. Evelyn CR, Wade SM, Wang Q, Wu M, Iñiguez-Lluhí JA, Merajver SD, Neubig RR.  (2007)  CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling..  Mol Cancer Ther,  (8): (2249-60).  [PMID:17699722]

Solution Calculators