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CCG 203971 - 10mM in DMSO, high purity , CAS No.1443437-74-8
Inhibits the MRTF/SRF gene transcription pathway; antifibrotic agent
Basic Description Synonyms N-(4-Chlorophenyl)-1-[3-(2-furanyl)benzoyl]-3-piperidinecarboxamide；CCG-203971；N-(4-Chlorophenyl)-1-[3-(2-furanyl)benzoyl]-3-piperidinecarboxamide； CCG 203971, CCG-203971, CCG-203971 CCG 203971；CCG203971;N-(4-chlorophenyl)-1-(3-(furan-2-yl)benzoyl)piperid Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms Antifibrotic agent; inhibits fibrosis by targeting the MRTF/SRF gene transcription pathway. Selectively inhibits proliferation of SSc-derived dermal fibroblasts but not that of normal fibroblasts. Inhibits expression of CTGF,α-SMA, and COL1A2 in SSc fibr Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™
Names and Identifiers IUPAC Name N-(4-chlorophenyl)-1-[3-(furan-2-yl)benzoyl]piperidine-3-carboxamide INCHI InChI=1S/C23H21ClN2O3/c24-19-8-10-20(11-9-19)25-22(27)18-6-2-12-26(15-18)23(28)17-5-1-4-16(14-17)21-7-3-13-29-21/h1,3-5,7-11,13-14,18H,2,6,12,15H2,(H,25,27) InChi Key HERLZBNILRVHQN-UHFFFAOYSA-N Canonical SMILES C1CC(CN(C1)C(=O)C2=CC=CC(=C2)C3=CC=CO3)C(=O)NC4=CC=C(C=C4)Cl Isomeric SMILES C1CC(CN(C1)C(=O)C2=CC=CC(=C2)C3=CC=CO3)C(=O)NC4=CC=C(C=C4)Cl PubChem CID 71681561 MeSH Entry Terms CCG-203971;N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide Molecular Weight 408.88
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