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CCR6 inhibitor 1 - 99%, high purity , CAS No.2437547-04-9

  • ≥99%
Item Number
C650442
Grouped product items
SKUSizeAvailabilityPrice Qty
C650442-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$450.90
C650442-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$750.90
C650442-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,950.90
C650442-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,300.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsCCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC 50 s of 0.45 and 6 nM for monkey and human CCR6 , much more selective at CCR6 over human CCR1 (IC 50 , > 30000 nM), and CCR7 (IC 50 , 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phospho
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC 50 s of 0.45 and 6 nM for monkey and human CCR6 , much more selective at CCR6 over human CCR1 (IC 50 , > 30000 nM), and CCR7 (IC 50 , 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer

In Vitro

CCR6 inhibitor 1 (Compound 35) inhibits L20-induced human B cell migration. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Moneky CCR6 0.45 nM (IC 50 ) Human CCR6 6 nM (IC 50 ) Human CCR7 9400 nM (IC 50 )

AI Insight

Names and Identifiers

Canonical SMILES O=S([C@H](CC1)CC[C@@H]1NC2=NC=C(C(F)(F)F)C=C2)(C3=CC=C(C4=CC=NC(C(N)=O)=C4)C=C3)=O
Molecular Weight 504.52

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

SolubilityDMSO : ≥ 125 mg/mL (247.76 mM)

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