Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C286997-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $107.90 | |
C286997-10mg | 10mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $173.90 | |
C286997-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $347.90 | |
C286997-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $587.90 | |
C286997-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,058.90 |
Potent and selective RXRα agonist
Synonyms | 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid;CD3254 ;(E)-3-(4-hydroxy-3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl)acrylic acid; |
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Specifications & Purity | Moligand™, ≥95% |
Biochemical and Physiological Mechanisms | Selective RXRαagonist; exhibits no activity at RARα, RARβor RARγreceptors. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of Retinoid X receptor-α |
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IUPAC Name | (E)-3-[4-hydroxy-3-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)phenyl]prop-2-enoic acid |
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INCHI | InChI=1S/C24H28O3/c1-15-12-19-20(24(4,5)11-10-23(19,2)3)14-17(15)18-13-16(6-8-21(18)25)7-9-22(26)27/h6-9,12-14,25H,10-11H2,1-5H3,(H,26,27)/b9-7+ |
InChi Key | DYLLZSVPAUUSSB-VQHVLOKHSA-N |
Canonical SMILES | CC1=CC2=C(C=C1C3=C(C=CC(=C3)C=CC(=O)O)O)C(CCC2(C)C)(C)C |
Isomeric SMILES | CC1=CC2=C(C=C1C3=C(C=CC(=C3)/C=C/C(=O)O)O)C(CCC2(C)C)(C)C |
PubChem CID | 44566110 |
Molecular Weight | 364.48 |
PubChem CID | 44566110 |
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ChEMBL Ligand | CHEMBL491294 |
CAS Registry No. | 196961-43-0 |
RCSB PDB Ligand | 2E3 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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E23151128 | Certificate of Analysis | Mar 23, 2023 | C286997 |
E23151136 | Certificate of Analysis | Mar 23, 2023 | C286997 |
E23151140 | Certificate of Analysis | Mar 23, 2023 | C286997 |
E23151148 | Certificate of Analysis | Mar 23, 2023 | C286997 |
E23151149 | Certificate of Analysis | Mar 23, 2023 | C286997 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 36.45, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 36.45, Max Conc. mM: 100 |
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1. le Maire A, Grimaldi M, Roecklin D, Dagnino S, Vivat-Hannah V, Balaguer P, Bourguet W. (2009) Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors.. EMBO Rep, 10 (4): (367-73). [PMID:19270714] |