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CD155/PVR Rat mAb

  • Azide Free
  • Carrier Free
  • ExactAb™
  • Low Endotoxin
  • Validated
  • ≥95%(SDS-PAGE&HPLC)
  • Lot by Lot
Features and benefits
  • Short Overview:

    mAb (4.24); Rat anti Mouse CD155/PVR Antibody; WB, Functional Assays, Flow; Unconjugated

  • Species reactivity(Reacts with): Mouse
  • Isotype: Rat IgG2a
    Application:
  • Flow Cytometry
  • Functional Assay
  • WB
Item Number
Ab122568
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab122568-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab122568-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$169.90
Ab122568-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$219.90
Ab122568-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

mAb (4.24); Rat anti Mouse CD155/PVR Antibody; WB, Functional Assays, Flow; Unconjugated

Basic Description

Product NameCD155/PVR Rat mAb
Specifications & PurityExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, ≥95%(SDS-PAGE&HPLC), Lot by Lot
Host speciesRat
SpecificityCD155/PVR
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Low Endotoxin, Validated
Product Description

Rat anti Mouse CD155/PVR Antibody, Monoclonal (4.24), could be used for WB, Functional Assays, Flow and so on.
Application

WB: Use at an assay dependent concentration.

Functional Assays: Use at an assay dependent concentration.

Flow: Use at an assay dependent concentration.
Protein Function
Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.

Product Properties

IsotypeRat IgG2a
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein G purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

CD155/PVR Rat mAb (Ab122568) - Flow Cytometry
Flow Cytometry analysis of thymocytes cells labelling CD155/PVR (red) with CD155/PVR Rat mAb (Ab122568) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.

Application

ApplicationDilution info
WB

Use at an assay dependent concentration.

Functional Assays

Use at an assay dependent concentration.

Flow

Use at an assay dependent concentration.

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Solution Calculators