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CD18 Rat mAb - Primary antibody, specific to CD18, Rat IgG2a

  • Azide Free
  • Carrier Free
  • Validated
  • ≥95%(SDS-PAGE)
  • Lot by Lot
Features and benefits
  • Short Overview:

    mAb (M18/2); Rat anti Mouse CD18 Antibody; in vivo LFA-1 neutralization, Flow; Unconjugated

  • Species reactivity(Reacts with): Mouse
  • Isotype: Rat IgG2a
    Application:
  • Animal Model
  • Flow Cytometry
  • Functional Assay
  • Neutralization
Item Number
Ab094077
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab094077-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
Ab094077-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab094077-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
Ab094077-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$219.90

mAb (M18/2); Rat anti Mouse CD18 Antibody; in vivo LFA-1 neutralization, Flow; Unconjugated

Basic Description

Product NameCD18 Rat mAb - Primary antibody, specific to CD18, Rat IgG2a
Specifications & PurityCarrier Free, Validated, Azide Free, ≥95%(SDS-PAGE), Lot by Lot
Host speciesRat
SpecificityCD18
ImmunogenC57BL/10 splenocytes
ConjugationUnconjugated
GradeAzide Free, Carrier Free, Validated
Product Description

Rat anti Mouse CD18 Antibody, Monoclonal (M18/2), could be used for in vivo LFA-1 neutralization, Flow and so on.
Application
Flow: Use at an assay dependent concentration.
in vivo LFA-1 neutralization: Use at an assay dependent concentration.
Protein Function
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Product Properties

IsotypeRat IgG2a
Light Chain Typekappa
Purification MethodProtein G purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at 2-8°C,Freeze prohibited
Shipped InWet ice
Stability And StorageShipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.

Images

CD18 Rat mAb (Ab094077) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling CD18 with CD18 Rat mAb (Ab094077) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).

CD18 Rat mAb (Ab094077) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling CD18 (red) with CD18 Rat mAb (Ab094077) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets

ITGB2 Tclin Integrin beta-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
Flow

Use at an assay dependent concentration.

in vivo LFA-1 neutralization

Use at an assay dependent concentration.

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0607307Certificate of AnalysisJun 25, 2024 Ab094077
ZJ24F0607306Certificate of AnalysisJun 25, 2024 Ab094077
ZJ24F0607305Certificate of AnalysisJun 25, 2024 Ab094077

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