CD18 Rat mAb - Primary antibody, specific to CD18, Rat IgG2a
Specifications & Purity
Carrier Free, Validated, Azide Free, ≥95%(SDS-PAGE), Lot by Lot
Host species
Rat
Specificity
CD18
Immunogen
C57BL/10 splenocytes
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, Validated
Product Description
Rat anti Mouse CD18 Antibody, Monoclonal (M18/2), could be used for in vivo LFA-1 neutralization, Flow and so on. Application Flow: Use at an assay dependent concentration. in vivo LFA-1 neutralization: Use at an assay dependent concentration. Protein Function Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.
Product Properties
Isotype
Rat IgG2a
Light Chain Type
kappa
Purification Method
Protein G purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at 2-8°C,Freeze prohibited
Shipped In
Wet ice
Stability And Storage
Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.
Images
CD18 Rat mAb (Ab094077) - Flow Cytometry Flow Cytometry analysis of mouse splenocytes cells labelling CD18 with CD18 Rat mAb (Ab094077) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).
CD18 Rat mAb (Ab094077) - Flow Cytometry Flow Cytometry analysis of mouse splenocytes cells labelling CD18 (red) with CD18 Rat mAb (Ab094077) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.