mAb (EBVCS-5); Mouse anti Human CD23 Antibody; Flow; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab094310-10μg | 10μg | In stock | $26.90 | |
| Ab094310-50μg | 50μg | In stock | $79.90 | |
| Ab094310-100μg | 100μg | In stock | $119.90 | |
| Ab094310-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $999.90 |
mAb (EBVCS-5); Mouse anti Human CD23 Antibody; Flow; Unconjugated
| Product Name | CD23 Mouse mAb - Primary antibody, specific to CD23, Mouse IgG1 |
|---|---|
| Synonyms | BLAST-2; CD23; CD23A; CD23CD23 antigen; CLEC4J; CLEC4JC-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon RII; Fc fragment of IgE, low affinity II, receptor for (CD23); FCE2Fc fragment of IgE, low affinity II, recep |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot |
| Host species | Mouse |
| Specificity | CD23 |
| Immunogen | Recombinant protein of human CD23 |
| Positive Control | Flow: Human peripheral blood lymphocytes. |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Validated |
| Product Description | Mouse anti Human CD23 Antibody, Monoclonal (EBVCS-5), could be used for Flow and so on. |
| Isotype | Mouse IgG1 |
|---|---|
| Light Chain Type | Kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein G purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Stability And Storage | Shipped at 4°C. Store at 4°C long term (12 months). Upon delivery aliquot. |
CD23 Mouse mAb (Ab094310) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD23 with CD23 Mouse mAb (Ab094310) conjugated with biotin (right panel) at 0.1 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156250).
CD23 Mouse mAb (Ab094310) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD23 (red) with CD23 Mouse mAb (Ab094310) conjugated with biotin at 0.1 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156250). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
CD23 Mouse mAb (Ab094310) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD23 (red) with CD23 Mouse mAb (Ab094310) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (Alexa Fluor® 647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| Flow | 1μg/100w cells |
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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0404407 | Certificate of Analysis | Apr 10, 2024 | Ab094310 |
| ZJ24F0404406 | Certificate of Analysis | Apr 10, 2024 | Ab094310 |
| ZJ24F0404405 | Certificate of Analysis | Apr 10, 2024 | Ab094310 |
| 1. Yokota A, Kikutani H, Tanaka T, Sato R, Barsumian EL, Suemura M, Kishimoto T. (1988) Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression.. Cell, 55 (4): (611-8). [PMID:2972386] |
| 2. Rose, K K and 8 more authors.. (1992) Partial characterization of natural and recombinant human soluble CD23.. The Biochemical journal, (15): [PMID:1417742] |
| 3. Pirron, U U, Schlunck, T T, Prinz, J C JC and Rieber, E P EP.. (1990) IgE-dependent antigen focusing by human B lymphocytes is mediated by the low-affinity receptor for IgE.. European journal of immunology, [PMID:2167225] |
| 4. Kikutani, H H and 9 more authors.. (1986) Molecular structure of human lymphocyte receptor for immunoglobulin E.. Cell, (5): [PMID:2877743] |
| 5. Ikuta, K K and 7 more authors.. (1987) Human lymphocyte Fc receptor for IgE: sequence homology of its cloned cDNA with animal lectins.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2949326] |
| 6. Lüdin, C C and 8 more authors.. (1987) Cloning and expression of the cDNA coding for a human lymphocyte IgE receptor.. The EMBO journal, [PMID:3034567] |
| 7. Vouldoukis, I I and 7 more authors.. (1995) The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:7544003] |
| 8. Padlan, E A EA and Helm, B A BA.. (1993) Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23).. Receptor, [PMID:8142907] |
| 9. Bajorath, J J and Aruffo, A A.. (1996) Structure-based modeling of the ligand binding domain of the human cell surface receptor CD23 and comparison of two independently derived molecular models.. Protein science : a publication of the Protein Society, [PMID:8745401] |
| 10. Grimwood, Jane J and 97 more authors.. (2004) The DNA sequence and biology of human chromosome 19.. Nature, (1): [PMID:15057824] |
| 11. Hibbert, Richard G RG and 9 more authors.. (2005) The structure of human CD23 and its interactions with IgE and CD21.. The Journal of experimental medicine, (19): [PMID:16172256] |
| 12. Wurzburg, Beth A BA, Tarchevskaya, Svetlana S SS and Jardetzky, Theodore S TS.. (2006) Structural changes in the lectin domain of CD23, the low-affinity IgE receptor, upon calcium binding.. Structure (London, England : 1993), [PMID:16765898] |
| 13. Lemieux, George A GA and 9 more authors.. (2007) The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.. The Journal of biological chemistry, (18): [PMID:17389606] |
| 14. Pathan, Nuzhat I NI and 5 more authors.. (2008) Mediation of apoptosis by and antitumor activity of lumiliximab in chronic lymphocytic leukemia cells and CD23+ lymphoma cell lines.. Blood, (1): [PMID:18032710] |
| 15. Ivaldi, Corinne C and 6 more authors.. (2012) Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23.. PloS one, [PMID:22615937] |
| 16. Hersheson, Joshua J and 17 more authors.. (2013) Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia.. Annals of neurology, [PMID:23424103] |
