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CD33 Mouse mAb - Primary antibody, specific to CD33, Mouse IgG1

  • Carrier Free
  • ExactAb™
  • Validated
  • Lot by Lot
Features and benefits
  • Short Overview:

    mAb (HIM3-4); Mouse anti Human CD33 Antibody; Flow; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
    Application:
  • Flow Cytometry
Item Number
Ab006571
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab006571-10μg
10μg
In stock
$26.90
Ab006571-50μg
50μg
In stock
$69.90
Ab006571-100μg
100μg
In stock
$99.90
Ab006571-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90

mAb (HIM3-4); Mouse anti Human CD33 Antibody; Flow; Unconjugated

View related series
Accession#:P20138 CD33 Gene ID:945

Basic Description

Product NameCD33 Mouse mAb - Primary antibody, specific to CD33, Mouse IgG1
SynonymsCD33 antigen (gp67); CD33 antigen; CD33 molecule; CD33; FLJ00391; gp67; myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; Sialic acid-binding Ig-like lectin 3; Siglec3; Siglec-3; SIGLEC3gp67; CD 33 antibody; CD33 antibody; CD33
Specifications & PurityExactAb™, Validated, Carrier Free, Lot by Lot
Host speciesMouse
SpecificityCD33
ImmunogenNFMY-9s human cell line.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Mouse anti Human CD33 Antibody, Monoclonal (HIM3-4), could be used for Flow and so on.
Application:
Flow: < 0.5 μg/100w cells
Protein Function
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Product Properties

IsotypeMouse IgG1
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at 2-8°C
Shipped InWet ice
Stability And StorageShipped at 4°C. Store at 4°C long term (36 months). Upon delivery aliquot.

Images

CD33 Mouse mAb (Ab006571) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD33 with CD33 Mouse mAb (Ab006571) conjugated with biotin (right panel) at 0.1 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156250).

CD33 Mouse mAb (Ab006571) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD33 (red) with CD33 Mouse mAb (Ab006571) conjugated with biotin at 0.1 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156250). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

CD33 Mouse mAb (Ab006571) - Flow Cytometry
Flow Cytometry analysis of K562 cells labelling CD33 (red) with CD33 Mouse mAb (Ab006571) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (Alexa Fluor® 647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets

CD33 Tclin Myeloid cell surface antigen CD33 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
Flow

< 0.5µg/100w cells

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0102470Certificate of AnalysisJan 18, 2024 Ab006571
ZJ24F0102469Certificate of AnalysisJan 18, 2024 Ab006571
ZJ24F0102468Certificate of AnalysisJan 18, 2024 Ab006571

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