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CD40 Mouse mAb - Primary antibody, specific to CD40, Mouse IgG2b

  • Carrier Free
  • ExactAb™
  • Validated
  • Lot by Lot
Features and benefits
  • Short Overview:

    mAb (HI40a); Mouse anti Human CD40 Antibody; Flow; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG2b
    Application:
  • Flow Cytometry
Item Number
Ab094763
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab094763-10μg
10μg
In stock
$26.90
Ab094763-50μg
50μg
In stock
$69.90
Ab094763-100μg
100μg
In stock
$99.90
Ab094763-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90

mAb (HI40a); Mouse anti Human CD40 Antibody; Flow; Unconjugated

View related series
Accession#:P25942 CD40 Gene ID:958

Basic Description

Product NameCD40 Mouse mAb - Primary antibody, specific to CD40, Mouse IgG2b
SynonymsB cell surface antigen CD40; B-cell surface antigen CD40; Bp50B cell-associated molecule; CD40 antigen; CD40 molecule, TNF receptor superfamily member 5; CD40 type II isoform; CD40; CD40L receptor; CDw40; MGC9013; nerve growth factor receptor-related B-ly
Specifications & PurityExactAb™, Validated, Carrier Free, Lot by Lot
Host speciesMouse
SpecificityCD40
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Mouse anti Human CD40 Antibody, Monoclonal (HI40a), could be used for Flow and so on.

Application:

Flow: < 0.5 μg/100w cells

Protein Function

Receptor for TNFSF5/CD40LG.

Product Properties

IsotypeMouse IgG2b
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at 2-8°C
Shipped InWet ice
Stability And StorageShipped at 4°C. Store at 4°C long term (36 months). Upon delivery aliquot.

Images

CD40 Mouse mAb (Ab094763) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD40 (red) with CD40 Mouse mAb (Ab094763) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (Alexa Fluor® 647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets

CD40 Tchem Tumor necrosis factor receptor superfamily member 5 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
Flow

< 0.5µg/100w cells

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0102452Certificate of AnalysisJan 18, 2024 Ab094763
ZJ24F0102451Certificate of AnalysisJan 18, 2024 Ab094763
ZJ24F0102450Certificate of AnalysisJan 18, 2024 Ab094763

Related Documents

References

1. Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J.  (2001)  The DNA sequence and comparative analysis of human chromosome 20..  Nature,  414  (6866): (865-71).  [PMID:11780052]
2. Chen J, Song Y, Bojadzic D, Tamayo-Garcia A, Landin AM, Blomberg BB, Buchwald P..  (2017)  Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction..  J Med Chem,  60  (21): (8906-8922).  [PMID:29024591]
3. Braesch-Andersen, S S and 5 more authors..  (1989)  Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40..  Journal of immunology (Baltimore, Md. : 1950),    (15):   [PMID:2463309]
4. Stamenkovic, I I, Clark, E A EA and Seed, B B..  (1989)  A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas..  The EMBO journal,      [PMID:2475341]
5. Sato, T T, Irie, S S and Reed, J C JC..  (1995)  A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40..  FEBS letters,    (23):   [PMID:7530216]
6. Cheng, G G and 5 more authors..  (1995)  Involvement of CRAF1, a relative of TRAF, in CD40 signaling..  Science (New York, N.Y.),    (10):   [PMID:7533327]
7. Bajorath, J J and Aruffo, A A..  (1997)  Construction and analysis of a detailed three-dimensional model of the ligand binding domain of the human B cell receptor CD40..  Proteins,      [PMID:9037712]
8. Kashiwada, M M and 8 more authors..  (1998)  Tumor necrosis factor receptor-associated factor 6 (TRAF6) stimulates extracellular signal-regulated kinase (ERK) activity in CD40 signaling along a ras-independent pathway..  The Journal of experimental medicine,    (19):   [PMID:9432981]
9. Mizushima, S S and 8 more authors..  (1998)  Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5)..  Gene,    (30):   [PMID:9511754]
10. Singh, J J and 7 more authors..  (1998)  The role of polar interactions in the molecular recognition of CD40L with its receptor CD40..  Protein science : a publication of the Protein Society,      [PMID:9605317]
11. Pullen, S S SS and 5 more authors..  (1998)  CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization..  Biochemistry,    (25):   [PMID:9718306]
12. Ni, C Z CZ and 6 more authors..  (2000)  Molecular basis for CD40 signaling mediated by TRAF3..  Proceedings of the National Academy of Sciences of the United States of America,    (12):   [PMID:10984535]
13. Tone, M M, Tone, Y Y, Fairchild, P J PJ, Wykes, M M and Waldmann, H H..  (2001)  Regulation of CD40 function by its isoforms generated through alternative splicing..  Proceedings of the National Academy of Sciences of the United States of America,    (13):   [PMID:11172023]
14. Ferrari, S S and 15 more authors..  (2001)  Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM..  Proceedings of the National Academy of Sciences of the United States of America,    (23):   [PMID:11675497]
15. Khandekar, S S SS and 9 more authors..  (2001)  Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells..  Protein expression and purification,      [PMID:11676606]
16. Li, Chenglong C and 9 more authors..  (2002)  Downstream regulator TANK binds to the CD40 recognition site on TRAF3..  Structure (London, England : 1993),      [PMID:12005438]
17. Tai, Yu-Tzu YT and 13 more authors..  (2004)  Mechanisms by which SGN-40, a humanized anti-CD40 antibody, induces cytotoxicity in human multiple myeloma cells: clinical implications..  Cancer research,    (15):   [PMID:15087402]
18. Zhang, Zemin Z and Henzel, William J WJ..  (2004)  Signal peptide prediction based on analysis of experimentally verified cleavage sites..  Protein science : a publication of the Protein Society,      [PMID:15340161]
19. Ouadani, Hanen H and 14 more authors..  (2016)  Novel and recurrent AID mutations underlie prevalent autosomal recessive form of HIGM in consanguineous patients..  Immunogenetics,      [PMID:26545377]
20. Takada, Yoko K; Yu, Jessica; Shimoda, Michiko and Takada, Yoshikazu..  (2019)  Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling..  Journal of immunology (Baltimore, Md. : 1950),    (1):   [PMID:31331973]

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