ExactAb™, Validated, Carrier Free, Azide Free, Lot by Lot
Host species
Rat
Specificity
CD45
Immunogen
Mouse lymphoma cell line
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, ExactAb™, Validated
Product Description
Rat anti Mouse CD45 Antibody, Monoclonal (I3/2.3), could be used for Flow and so on.
Application
Flow: 1.0 μg/100w cells
Protein Function
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.
Product Properties
Isotype
Rat IgG2b
SDS-PAGE
150 kDa
Purification Method
Protein G purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Stability And Storage
Shipped at 4°C. Store at 4°C long term (12 months). Upon delivery aliquot.
Images
CD45 Rat mAb (Ab094914) - Flow Cytometry Flow Cytometry analysis of mouse splenocytes cells labelling CD45 with CD45 Rat mAb (Ab094914) conjugated with biotin (right panel) at 0.2 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) - Isotype Control (left panel) and detected with SA-PE (rp156250).
CD45 Rat mAb (Ab094914) - Flow Cytometry Flow Cytometry analysis of mouse splenocytes cells labelling CD45 (red) with CD45 Rat mAb (Ab094914) conjugated with biotin at 0.2 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156250). Blue - Isotype control, Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.
Associated Targets(Human)
PTPRCTchemReceptor-type tyrosine-protein phosphatase C (0 Activities)