Rat anti Mouse/Human CD45R Antibody, Monoclonal (RA3-6B2), could be used for WB, Flow, IHC, IP, ICC, IF, ELISA,Functional Assays and so on. Application Flow: 0.125µg/100w cells IHC: 5.0µg/mL WB: Use at an assay dependent concentration. IP: Use at an assay dependent concentration. ICC/IF: Use at an assay dependent concentration. ELISA: Use at an assay dependent concentration. Functional Assays: Use at an assay dependent concentration. Protein Function Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.
Product Properties
Isotype
Rat IgG2a
Light Chain Type
kappa
SDS-PAGE
26.4 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 207.1 kDa, under non-reducing conditions.
Purification Method
Protein A purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Associated Targets
PTPRCTchem Receptor-type tyrosine-protein phosphatase C 0 Activities
ZJ24F0707947