CD47 Rat mAb - Primary antibody, specific to CD47, Rat IgG2a
Specifications & Purity
Validated, Azide Free, Carrier Free, ≥95%(SDS-PAGE), Lot by Lot
Host species
Rat
Specificity
CD47
Immunogen
Intact CD47 purified from placenta
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, Validated
Product Description
Rat anti Mouse CD47 Antibody, Monoclonal (MIAP301), could be used for Flow, in vivo CD47 blockade, in vitro CD47 blockade, IF, ICC and so on. Application Flow: Use at an assay dependent concentration. in vivo CD47 blockade: Use at an assay dependent concentration. in vitro CD47 blockade: Use at an assay dependent concentration. ICC/IF: Use at an assay dependent concentration. Protein Function Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Product Properties
Isotype
Rat IgG2a
Light Chain Type
kappa
Purification Method
Protein G purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at 2-8°C,Freeze prohibited
Shipped In
Wet ice
Stability And Storage
Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon delivery aliquot.
ZJ24F0707950