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Cerdulatinib - 98%, high purity , Tyrosine-protein kinase TYK2 inhibitor, CAS No.1198300-79-6, Tyrosine-protein kinase TYK2 inhibitor

Moligand™
≥98%

CAS#: 1198300-79-6
Formula: C₂₀H₂₇N₇O₃S
Molecular Weight: 445.54
PubChem CID: 44595079
PubChem SID: 488201014

Item Number

C413025

Grouped product items
SKU	Size	Availability	Price
C413025-10mg	10mg	In stock	$155.90
C413025-25mg	25mg	In stock	$351.90
C413025-50mg	50mg	In stock	$521.90
C413025-100mg	100mg	In stock	$808.90
C413025-200mg	200mg	In stock	$1,200.90

View related series

AMP kinase Inhibitor colony stimulating factor 1 receptor Inhibitor Janus kinase 1 Inhibitor Janus kinase 2 Inhibitor Janus kinase 3 Inhibitor mitogen-activated protein kinase kinase kinase 9 Inhibitor NUAK family kinase 1 Inhibitor serine/threonine kinase 4 Inhibitor spleen associated tyrosine kinase Inhibitor tyrosine kinase 2 Inhibitor

Basic Description

Synonyms	Cerdulatinib\|1198300-79-6\|Cerdulatinib (PRT062070)\|Cerdulatinib [INN]\|PRT062070\|UNII-D1LXQ45S1O\|D1LXQ45S1O\|4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide\|PRT-062070\|4-(Cyclopropylamino)-2-((4-(4-(ethanesulfonyl)p
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Cerdulatinib (PRT062070, PRT2070) is a potent and selective inhibitor of Tyk2 with IC50 of 0.5 nM. Cerdulatinib is also a dual inhibitor of JAK and SYK with IC50 of 12 nM, 6 nM, 8 nM and 32 nM for JAK1, JAK2, JAK3 and SYK, respectively.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Tyrosine-protein kinase TYK2 inhibitor

Associated Targets

CSF1R Tclin Macrophage colony-stimulating factor 1 receptor 1 Activities

Discover Target: CSF1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

STK4 Tchem Serine/threonine-protein kinase 4 1 Activities

Discover Target: STK4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TYK2 Tclin Non-receptor tyrosine-protein kinase TYK2 1 Activities

Discover Target: TYK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

JAK3 Tclin Tyrosine-protein kinase JAK3 2 Activities

Discover Target: JAK3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SYK Tclin Tyrosine-protein kinase SYK 1 Activities

Discover Target: SYK

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

JAK1 Tclin Tyrosine-protein kinase JAK1 2 Activities

Discover Target: JAK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NUAK1 Tchem NUAK family SNF1-like kinase 1 1 Activities

Discover Target: NUAK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

JAK2 Tclin Tyrosine-protein kinase JAK2 2 Activities

Discover Target: JAK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAP3K9 Tchem Mitogen-activated protein kinase kinase kinase 9 1 Activities

Discover Target: MAP3K9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488201014
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488201014
IUPAC Name	4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide
INCHI	InChI=1S/C20H27N7O3S/c1-2-31(29,30)27-11-9-26(10-12-27)16-7-5-15(6-8-16)24-20-22-13-17(18(21)28)19(25-20)23-14-3-4-14/h5-8,13-14H,2-4,9-12H2,1H3,(H2,21,28)(H2,22,23,24,25)
InChi Key	BGLPECHZZQDNCD-UHFFFAOYSA-N
Canonical SMILES	CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N
Isomeric SMILES	CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N
PubChem CID	44595079
Molecular Weight	445.54

PubChem CID

44595079

CAS Registry No.

1198300-79-6

PubChem SID

488201014

Certificates

Certificate of Analysis(COA)

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10 results found

Lot Number	Certificate Type	Date	Item
D2328201	Certificate of Analysis	Mar 24, 2023	C413025
D2328204	Certificate of Analysis	Mar 24, 2023	C413025
D2328206	Certificate of Analysis	Mar 24, 2023	C413025
D2328211	Certificate of Analysis	Mar 24, 2023	C413025
D2328212	Certificate of Analysis	Mar 24, 2023	C413025
D2328217	Certificate of Analysis	Mar 24, 2023	C413025
D2328218	Certificate of Analysis	Mar 24, 2023	C413025
E2304142	Certificate of Analysis	Mar 24, 2023	C413025
E2304147	Certificate of Analysis	Mar 24, 2023	C413025
E2304162	Certificate of Analysis	Mar 24, 2023	C413025

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