Cevidoplenib - 98%, high purity , CAS No.1703788-21-9

Item Number

C648806

Grouped product items
SKU	Size	Availability	Price
C648806-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$380.90
C648806-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$600.90
C648806-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,150.90
C648806-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,800.90

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Basic Description

Synonyms	Cevidoplenib\|Cevidoplenib [INN]\|1703788-21-9\|3N3H8BX897\|UNII-3N3H8BX897\|Methanone, cyclopropyl(5-((4-(4-(((4S)-4-hydroxy-2-isoxazolidinyl)methyl)-3-methyl-1H-pyrazol-1-yl)-2-pyrimidinyl)amino)-1-methyl-1H-indol-3-yl)-\|cyclopropyl-[5-[[4-[4-[[(4S)-4-hydrox
Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Cevidoplenib is an orally available inhibitor of spleen tyrosine kinase (Syk) , with potential anti-inflammatory and immunomodulating activities. In Vivo Upon oral administration, cevidoplenib binds to and inhibits the activity of SYK, blocking Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, neutrophils, mast cells, natural killer (NK) cells and B cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Names and Identifiers

IUPAC Name	cyclopropyl-[5-[[4-[4-[[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]methyl]-3-methylpyrazol-1-yl]pyrimidin-2-yl]amino]-1-methylindol-3-yl]methanone
INCHI	InChI=1S/C25H27N7O3/c1-15-17(10-31-12-19(33)14-35-31)11-32(29-15)23-7-8-26-25(28-23)27-18-5-6-22-20(9-18)21(13-30(22)2)24(34)16-3-4-16/h5-9,11,13,16,19,33H,3-4,10,12,14H2,1-2H3,(H,26,27,28)/t19-/m0/s1
InChi Key	YCZUBLQESBVOSH-IBGZPJMESA-N
Canonical SMILES	CC1=NN(C=C1CN2CC(CO2)O)C3=NC(=NC=C3)NC4=CC5=C(C=C4)N(C=C5C(=O)C6CC6)C
Isomeric SMILES	CC1=NN(C=C1CN2C[C@@H](CO2)O)C3=NC(=NC=C3)NC4=CC5=C(C=C4)N(C=C5C(=O)C6CC6)C
Alternate CAS	1703788-21-9
PubChem CID	91754477
MeSH Entry Terms	cevidoplenib;cyclopropyl-(5-((4-(4-(((4S)-4-hydroxy-1,2-oxazolidin-2-yl)methyl)-3-methylpyrazol-1-yl)pyrimidin-2-yl)amino)-1-methylindol-3-yl)methanone;SKI-O-703
Molecular Weight	473.53

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Basic Description