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CGP 3466B maleate - ≥99%(HPLC), high purity , CAS No.200189-97-5

  • ≥99%(HPLC)
Item Number
C288106
Grouped product items
SKUSizeAvailabilityPrice Qty
C288106-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$86.90
C288106-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$140.90
C288106-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$271.90
C288106-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$434.90
C288106-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$706.90

GAPDH inhibitor; neuroprotective

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Dehydrogenases

Basic Description

SynonymsOmigapil maleate|200189-97-5|CGP 3466B maleate|CGP 3466B|Omigapil (Maleate)|CGP-3466B|TCH-346|UNII-3Q69BFZ4OP|3Q69BFZ4OP|Dibenzo(b,f)oxepin-10-ylmethyl-methyl-prop-2-ynyl-amine maleate|200189-97-5 (maleate)|N-(Dibenz(b,f)oxepin-10-ylmethyl)-N-methyl-N-(2-
Specifications & Purity≥99%(HPLC)
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Omigapil maleate, a GAPDH nitrosylation inhibitor, abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD).

Names and Identifiers

IUPAC Name N-(benzo[b][1]benzoxepin-5-ylmethyl)-N-methylprop-2-yn-1-amine;(Z)-but-2-enedioic acid
INCHI InChI=1S/C19H17NO.C4H4O4/c1-3-12-20(2)14-16-13-15-8-4-6-10-18(15)21-19-11-7-5-9-17(16)19;5-3(6)1-2-4(7)8/h1,4-11,13H,12,14H2,2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChi Key SQAZQLMBEHYFJA-BTJKTKAUSA-N
Canonical SMILES CN(CC#C)CC1=CC2=CC=CC=C2OC3=CC=CC=C31.C(=CC(=O)O)C(=O)O
Isomeric SMILES CN(CC#C)CC1=CC2=CC=CC=C2OC3=CC=CC=C31.C(=C\C(=O)O)\C(=O)O
PubChem CID 9821821
Molecular Weight 391.42

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 3.91, Max Conc. mM: 10; Solvent:DMSO, Max Conc. mg/mL: 39.14, Max Conc. mM: 100
SensitivityMoisture sensitive

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