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CHAPS - reagent grade,96%, high purity , CAS No.75621-03-3

  • AR
  • ≥96%
Item Number
C141274
Grouped product items
SKUSizeAvailabilityPrice Qty
C141274-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$9.90
C141274-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$35.90
C141274-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$126.90
C141274-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$356.90
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Zwitterionic non-denaturing detergent for solubilizing membrane proteins

View related series
Polymer / polymer reagent Steroids

Basic Description

SynonymsCHAPS|75621-03-3|3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE|3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate|CHEBI:1418|QBP25342AG|3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,
Specifications & Purityreagent grade,96%
Storage TempArgon charged
Shipped InNormal
GradeAR
Product Description

CHAPS is a non-denaturing, zwitterionic detergent derived from cholic acid. CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions and is electrically neutral. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. The critical micelle concentration of CHAPS is 6-10mM.
A non-denaturing, zwitterionic detergent for membrane proteins

Names and Identifiers

IUPAC Name 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate
INCHI InChI=1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
InChi Key UMCMPZBLKLEWAF-BCTGSCMUSA-N
Canonical SMILES CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
Isomeric SMILES C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C
WGK Germany 3
PubChem CID 107670
Molecular Weight 614.88

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
E2428156Certificate of AnalysisJun 06, 2024 C141274
E2428180Certificate of AnalysisJun 06, 2024 C141274
C2415010Certificate of AnalysisMar 18, 2024 C141274
D2409030Certificate of AnalysisMar 18, 2024 C141274
G23261005Certificate of AnalysisJul 27, 2023 C141274
E2305660Certificate of AnalysisMay 06, 2023 C141274
B23021222Certificate of AnalysisFeb 07, 2023 C141274
B2302926Certificate of AnalysisFeb 07, 2023 C141274
G2222467Certificate of AnalysisJul 29, 2022 C141274
G2222456Certificate of AnalysisJul 29, 2022 C141274
B2212183Certificate of AnalysisFeb 19, 2022 C141274
B2212184Certificate of AnalysisFeb 19, 2022 C141274

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Chemical and Physical Properties

SolubilitySoluble in water (10 mg/ml).
Sensitivitymoisture sensitive
Melt Point(°C)156-158℃

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

 SDS

 Specification Sheet

References

1. Awada Z et al..  (2019)  DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer..  Clin Epigenetics,  11  (138).  [PMID:31601247]

Solution Calculators

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