Chloramphenicol - Ready Made Solution, 100mg/mL in ethanol: isopropanol (95:5), ≥98% (HPLC), high purity , CAS No.56-75-7

Item Number

C476223

Grouped product items
SKU	Size	Availability	Price	Qty
C476223-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$39.90

Basic Description

Synonyms	chloramphenicol\|56-75-7\|Chloromycetin\|Chlornitromycin\|Levomycetin\|Chloroamphenicol\|Globenicol\|Halomycetin\|Levomicetina\|Oleomycetin\|Alficetyn\|Chloramex\|Chlorocid\|Chlorocol\|Fenicol\|Chloramficin\|Chloramfilin\|Enteromycetin\|Amphicol\|Aquamycetin\|Chloroptic\|Clor
Specifications & Purity	Moligand™, ≥98%(HPLC), Ready Made Solution, 100mg/mL in ethanol: isopropanol (95:5)
Biochemical and Physiological Mechanisms	1、Action mechanism: Chloramphenicol blocks the Peptidyl transferase step by combining with 50S Ribosome subunit and preventing aminoacyl tRNA from attaching to Ribosome, thus inhibiting the synthesis of bacterial protein. It also inhibits the synthesis of
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Application： Chloramphenicol is a synthetic antibiotic, which is isolated from Ziziphus veneeri. It usually takes 10-20 μ The concentration of g/mL is used for bacterial selection in molecular biology applications and as a selector for transformed cells containing Chloramphenicol resistance genes. Preparation instructions: This product is a ready made solution of 100 mg/mL in ethanol:isopropanol (95:5). It is shipped in dry ice and stored at -20°C. Explanation： Store in a closed container in a dry and ventilated place. Open containers must be carefully resealed and kept upright to prevent leakage. Storage level (TRGS 510): Flammable liquid ")

Names and Identifiers

IUPAC Name	2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
INCHI	InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1
InChi Key	WIIZWVCIJKGZOK-RKDXNWHRSA-N
Canonical SMILES	C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
Isomeric SMILES	C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
WGK Germany	3
RTECS	AB6825000
PubChem CID	5959
Molecular Weight	323.13
Beilstein	2225532

Sensitivity

Light sensitive

Specific Rotation[α]

20 ° (C=5, EtOH)

Flash Point(°F)

57.2°F closed cup

Flash Point(°C)

14.0°C closed cup

Melt Point(°C)

149-153°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Danger
Hazard Statements	H351:Suspected of causing cancer H318:Causes serious eye damage H317:May cause an allergic skin reaction H360:May damage fertility or the unborn child H350:May cause cancer H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help.
WGK Germany	3
RTECS	AB6825000
Merck Index	2077

References

1. Stephanie Petrella, Nathalie Ziental-Gelus, Claudine Mayer, Murielle Renard, Vincent Jarlier, Wladimir Sougakoff,. (2008-07-16) Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.. Antimicrobial agents and chemotherapy, 52 ((10)): ( 3725-3736 ). [PMID:18625772]

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Basic Description