CID-2858522 - ≥98%(HPLC), high purity , CAS No.758679-97-9

Item Number

C127807

Grouped product items
SKU	Size	Availability	Price
C127807-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$134.90
C127807-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$139.90
C127807-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$229.90
C127807-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$389.90

Selectively inhibits PKC-induced NF-κB activation

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Basic Description

Synonyms	758679-97-9\|CID-2858522\|1-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-(2-(3-hydroxypropylamino)-5,6-dimethyl-1H-benzo[d]imidazol-1-yl)ethanone\|CID2858522\|CID 2858522\|CHEMBL374350\|Z744D8S6JG\|ML029\|1-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypr
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Selectively inhibits protein kinase C (PKC)-induced activation of the NF-κB pathway (IC50< 0.1μM forPMA-stimulated IL-8 production). Inhibits antigen receptor-stimulated NF-κB activation in chronic lymphocytic leukemia (CLL) B cells. Does not inhibit othe
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	CID2858522

Names and Identifiers

IUPAC Name	1-(3,5-ditert-butyl-4-hydroxyphenyl)-2-[2-(3-hydroxypropylamino)-5,6-dimethylbenzimidazol-1-yl]ethanone
INCHI	InChI=1S/C28H39N3O3/c1-17-12-22-23(13-18(17)2)31(26(30-22)29-10-9-11-32)16-24(33)19-14-20(27(3,4)5)25(34)21(15-19)28(6,7)8/h12-15,32,34H,9-11,16H2,1-8H3,(H,29,30)
InChi Key	CYCGGKILBWERDJ-UHFFFAOYSA-N
Canonical SMILES	CC1=CC2=C(C=C1C)N(C(=N2)NCCCO)CC(=O)C3=CC(=C(C(=C3)C(C)(C)C)O)C(C)(C)C
Isomeric SMILES	CC1=CC2=C(C=C1C)N(C(=N2)NCCCO)CC(=O)C3=CC(=C(C(=C3)C(C)(C)C)O)C(C)(C)C
WGK Germany	3
PubChem CID	2858523
Molecular Weight	465.63

Safety and Hazards(GHS)

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H413:May cause long lasting harmful effects to aquatic life
Precautionary Statements	P273:Avoid release to the environment. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.
WGK Germany	3

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Basic Description