Cimaterol - 98%, high purity , CAS No.54239-37-1, Agonist of β 1-adrenoceptor;Agonist of β 2-adrenoceptor

Item Number

C140718

• Synonyms: cimaterol|54239-37-1|Cimater|Cimaterolum|AB-A 663|AC 263,780|2-amino-5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzonitrile|ABA-663|ZPY8VRF0GB|AC-263780|DTXSID2045652|AB-A 66|AB-A-66|Cimaterol D7|Benzonitrile, 2-amino-5-(1-hydroxy-2-((1-methylethyl)amino)eth
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: β adrenoceptor agonist (K i = 2.32 μM). Active in vivo .
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of β 1-adrenoceptor;Agonist of β 2-adrenoceptor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Cimaterol (CL 263780) is a β-adrenergic agonist on energy metabolism in ob/ob mice. The Kd for Cimaterol binding to the L6 β-receptor is 26 nM which is compatible with its EC50 for the stimulation of protein synthesis (approx 5 nM).